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American Focus > Blog > Tech and Science > Here’s how honeyeaters and other birds thrive on sugary diets
Tech and Science

Here’s how honeyeaters and other birds thrive on sugary diets

Last updated: February 26, 2026 1:40 pm
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Here’s how honeyeaters and other birds thrive on sugary diets
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The evolution of birds that feed on nectar and fruits has been a fascinating subject of study, shedding light on how these animals have adapted to a sugar-filled diet. Recent findings published in the journal Science have revealed that birds with such diets have developed unique genetic traits that allow them to thrive on high sugar intake.

Several groups of birds, including parrots, hummingbirds, honeyeaters, and sunbirds, have evolved to consume nectar and fruits, which are rich in sugars. Interestingly, these birds exhibit variants in genes that regulate metabolism, fat processing, and even blood pressure. Unlike mammals, birds have fasting blood glucose levels that are significantly higher, making them relatively insensitive to insulin.

In mammals, insulin plays a crucial role in regulating blood glucose levels by signaling a protein called GLUT4 to move to cell membranes, facilitating the absorption of sugar into cells. However, birds appear to lack this protein, leading to persistently high blood glucose levels. After feeding, hummingbirds, for example, experience a spike in blood sugar levels to levels that are more than twice as high as those observed in humans after a high-carb meal.

To understand how birds can thrive on such high sugar diets, researchers analyzed the genomes of various bird species with different dietary preferences. By comparing sugar-feeding species with those that prefer seeds, insects, or meat, the team identified thousands of genetic sequences that were altered in nectar-eating birds. These genetic changes were primarily located in regulatory regions of DNA that control gene expression and protein production. Additionally, nearly 600 genes were found to be involved in sugar and fat metabolism.

Interestingly, different groups of birds, such as parrots and sunbirds, exhibited similar genetic alterations due to their sugar-rich diets. Among the genes that were commonly altered in multiple high-sugar species, one gene stood out – MLXIPL. This gene, which codes for a transcription factor called ChREBP, serves as a cellular sugar sensor and plays a key role in regulating the activity of other genes involved in sugar metabolism.

Overall, these findings highlight the remarkable genetic adaptations that birds have undergone to thrive on sugar-filled diets. By unraveling the genetic mechanisms behind these adaptations, scientists can gain valuable insights into how different species have evolved to meet the unique challenges posed by their dietary preferences. As researchers continue to uncover the secrets of evolution, a recent study on hummingbirds has shed light on how these tiny birds have adapted to thrive on a diet of nectar and fruit. Led by biologist Maria Osipova and her colleagues, the study focused on the genetic changes that have occurred in hummingbirds to help them metabolize carbohydrates more efficiently.

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When Osipova and her team introduced the hummingbird gene MLXIPL into human cells, they observed a significant change in how the cells responded to sugar. The activation of genes involved in carbohydrate metabolism indicated that the birds have evolved a sophisticated system to process high levels of sugar in their diet.

Interestingly, most of the genetic changes observed in the hummingbirds were related to the regulation of other genes, rather than the production of specific proteins. This suggests that the birds have fine-tuned their genetic machinery to adapt to the demands of a high sugar diet, by modulating the responses of multiple genes simultaneously.

According to Chang Zhang, a physiologist involved in the study, the adaptations in hummingbirds go beyond just metabolism. The changes in gene expression also play a crucial role in controlling blood pressure, which is essential for maintaining the right consistency of blood plasma in the face of sticky sugar and high water intake.

The study highlights the complex interplay of genetic factors that have enabled hummingbirds to thrive on a diet that poses significant challenges to their physiology. Osipova suggests that genes like MLXIPL could be potential targets for treating metabolic diseases in humans, but emphasizes that a combination of genetic tweaks is needed to fully replicate the adaptations seen in hummingbirds.

In conclusion, the research on hummingbirds provides valuable insights into the mechanisms of evolution and adaptation in response to dietary challenges. By studying the genetic changes that have occurred in these birds, scientists can gain a better understanding of how complex biological systems have evolved to cope with different environmental pressures. The Importance of Mental Health Awareness

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TAGGED:BirdsDietsHereshoneyeatersSugaryThrive
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