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American Focus > Blog > Health and Wellness > Gender-affirming hormones protect from HIV, new data show
Health and Wellness

Gender-affirming hormones protect from HIV, new data show

Last updated: March 27, 2025 7:59 pm
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Gender-affirming hormones protect from HIV, new data show
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Over a decade ago, psychologist and researcher Jae Sevelius proposed the idea that the behaviors putting transgender individuals at a higher risk of contracting HIV were linked to the lack of gender affirmation they experienced. This theory, known as the gender affirmation framework, suggests that with proper medical care and validation from their support system, transgender individuals would be healthier overall and less likely to engage in risky behaviors.

A recent study published in The Lancet HIV involving over 8,000 trans and nonbinary individuals supports this concept. The study, conducted at LGBTQ+ community health centers in the U.S., found that patients receiving gender-affirming hormones were 37% less likely to be infected with HIV and 44% less likely to have transmissible levels of the virus in their blood. This significant impact reinforces the importance of gender affirmation in improving the health outcomes of transgender individuals.

Diana Tordoff, an epidemiologist at Stanford University, praised the study for confirming the hypothesis with a substantial effect size. The research comes at a crucial time when government actions have hindered research and clinical care for transgender individuals, denying variations in sex and restricting access to care.

The study, spanning from 2013 to 2019, focused on patients with diverse gender identities and racial backgrounds at specialized LGBTQ+ health centers in New York and Boston. It revealed disproportionately high rates of HIV among Black, Hispanic, and multiracial participants, possibly due to structural barriers like lower socioeconomic status.

Despite the positive outcomes of the study, challenges remain in conducting further research on transgender health. Sari Reisner, a social and psychiatric epidemiologist at the University of Michigan, highlighted the underinvestment in trans health and the limited data on trans individuals and HIV. The study also showed low uptake of pre-exposure prophylaxis (PrEP) among participants, indicating the need for more research on preventative measures.

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Looking ahead, researchers aim to investigate the mechanisms behind the associations between gender-affirming hormones and HIV risk among trans individuals. However, funding challenges pose a significant obstacle, with researchers like Reisner losing grants from the National Institutes of Health.

Despite these obstacles, experts emphasize the importance of prioritizing research on transgender health to improve outcomes and address disparities. The gender affirmation framework underscores the critical need for affirming gender identities to promote the well-being of transgender individuals and reduce their risk of HIV infection. The impact of climate change on global food security is becoming increasingly apparent as extreme weather events and shifting growing seasons disrupt crop production around the world. Climate change is altering the availability of water, temperature patterns, and the frequency of extreme weather events, all of which have significant implications for food production and distribution.

One of the key ways in which climate change is affecting food security is through changes in water availability. Droughts, floods, and changes in precipitation patterns are all becoming more frequent as a result of climate change. These events can lead to crop failures, reduced yields, and increased food insecurity in vulnerable regions. In places like sub-Saharan Africa, where agriculture is heavily dependent on rain-fed irrigation, these changes can have devastating effects on food production.

Rising temperatures are also impacting food security by altering the growing seasons of crops. Many crops have specific temperature requirements for optimal growth, and as temperatures rise, these requirements may no longer be met. This can lead to reduced yields and lower quality crops, further exacerbating food insecurity in already vulnerable regions.

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Extreme weather events, such as hurricanes, cyclones, and wildfires, are also becoming more common as a result of climate change. These events can destroy crops, damage infrastructure, and disrupt supply chains, leading to food shortages and price spikes. In 2017, for example, Hurricane Maria devastated Puerto Rico’s agriculture sector, leading to widespread food shortages on the island.

In addition to these direct impacts on food production, climate change is also affecting food distribution and access. As extreme weather events become more common, transportation routes may be disrupted, making it difficult to get food from farms to markets. This can lead to food shortages in urban areas and exacerbate food insecurity for vulnerable populations.

Addressing the impacts of climate change on food security will require a multi-faceted approach. Farmers will need to adopt more climate-resilient agricultural practices, such as planting drought-resistant crops and improving water management techniques. Governments will need to invest in infrastructure to protect against extreme weather events and support small-scale farmers who are most vulnerable to climate change.

International cooperation will also be crucial in addressing the global food security challenges posed by climate change. Developed countries will need to provide financial and technical assistance to developing countries to help them adapt to changing climate conditions and build more resilient food systems. In addition, efforts to reduce greenhouse gas emissions and mitigate the impacts of climate change will be essential in ensuring the long-term sustainability of the global food system.

Overall, the impacts of climate change on food security are becoming increasingly clear, and urgent action is needed to address these challenges. By taking proactive measures to build more resilient food systems and reduce greenhouse gas emissions, we can help ensure that future generations have access to a stable and secure food supply.

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