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American Focus > Blog > Health and Wellness > Study links diet quality to changes in oral microbiome
Health and Wellness

Study links diet quality to changes in oral microbiome

Last updated: April 14, 2025 4:53 pm
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Study links diet quality to changes in oral microbiome
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A groundbreaking study conducted by the University at Buffalo has shed light on the relationship between diet quality and the oral microbiome in postmenopausal women. Published in the Journal of Nutrition, the research revealed that women with healthier diets exhibited lower levels of certain bacteria in the oral microbiome, such as Streptococcus gordonii and Cardiobacterium species, which are linked to gum disease and heart infections, respectively.

The study, which involved 1,175 postmenopausal women, assessed their overall diet quality based on their adherence to the Healthy Eating Index 2020 (HEI-2020) guidelines. The findings showed that HEI-2020 scores were associated with the composition of the oral microbiome, with specific dietary components playing a significant role in influencing its diversity and composition. For example, the intake of total vegetables and protein foods was linked to more diverse oral microbiomes, while dairy and added sugar consumption was associated with less diversity.

Lead author Yihua Yue emphasized the importance of considering overall diet quality rather than individual nutrients in understanding the impact on the oral microbiome. The study aimed to determine if there were significant variations in the diversity and composition of the oral microbiome between individuals with high-quality versus low-quality diets. The results highlighted the potential influence of dietary patterns on oral health and underscored the importance of nutrition in preventing periodontal disease and related health conditions.

Amy Millen, the corresponding author of the study, emphasized the role of nutrition as a risk factor for inflammatory diseases, including periodontal disease. The research team aimed to provide additional evidence of the connection between diet quality and the oral microbiome to gain insights into the development of oral health conditions. The study findings suggested that certain dietary recommendations, such as reducing sugar intake and increasing vegetable consumption, could positively impact the oral microbiome composition.

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While the study focused on postmenopausal women due to their increased risk of gum disease and tooth loss, future research may explore a broader range of dietary habits and lifestyle factors. The authors recommended further investigations to evaluate the relevance of the HEI-2020 guidelines for oral health and to better understand the role of diet in shaping the oral microbiome.

In conclusion, this study offers valuable insights into the association between diet quality and the oral microbiome, highlighting the potential impact of dietary patterns on oral health. By emphasizing the importance of overall diet quality and specific dietary components, the research contributes to our understanding of how nutrition influences the oral microbiome and its implications for oral health outcomes.

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