Emergency Vaccination Efforts Reduce Deaths from Outbreaks by Nearly 60%
Emergency vaccination during outbreaks of diseases like cholera, Ebola, and measles has been instrumental in reducing deaths from such illnesses by almost 60% over the past 25 years, a recent study reveals.
The study, backed by the Gavi vaccine alliance and conducted in collaboration with researchers at the Burnet Institute in Australia, sheds light on the significant impact of emergency immunization efforts on public health and global health security.
Published in the British Medical Journal (BMJ) Global Health, the study examined 210 outbreaks of five infectious diseases in 49 lower-income countries between 2000 and 2023, including cholera, Ebola, measles, meningitis, and yellow fever.
The findings show that vaccine roll-outs during these outbreaks led to a substantial reduction in both infections and deaths, with nearly 60% decrease observed across the five diseases. The study also highlights the effectiveness of vaccination in preventing outbreaks from expanding.
Notably, vaccination efforts during yellow fever outbreaks resulted in a remarkable 99% decrease in deaths, while Ebola-related fatalities were reduced by 76%.
Moreover, the economic benefits of these immunization campaigns were substantial, estimated to have generated around $32 billion by averting deaths and years of life lost to disability. However, this figure may underestimate the total savings as it does not factor in outbreak response costs or broader societal and economic impacts of large-scale outbreaks.
For instance, the massive Ebola outbreak in West Africa in 2014, before the availability of approved vaccines, cost the affected countries over $53 billion, underscoring the importance of proactive vaccination strategies.
Amid rising global cases of vaccine-preventable diseases due to misinformation and cuts to international aid, organizations like Gavi play a crucial role in immunizing children worldwide. Gavi is currently seeking additional funding to continue its vital work in the face of dwindling support and recent funding cuts.

As the world grapples with the resurgence of preventable diseases, the study’s findings underscore the vital role of emergency vaccination campaigns in saving lives and curbing the spread of infectious diseases.