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American Focus > Blog > Health and Wellness > Colon cancer screening guideline change saved lives, studies say
Health and Wellness

Colon cancer screening guideline change saved lives, studies say

Last updated: August 4, 2025 11:45 am
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Colon cancer screening guideline change saved lives, studies say
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As the age for recommended screening was lowered from 50 to 45, an estimated 20 million Americans suddenly became eligible for screening “overnight.” This posed a challenge for health systems in terms of capacity and resources to meet the increased demand for colonoscopies and other screening methods.

Dr. Fola May, a cancer researcher and gastroenterologist at the University of California, Los Angeles, emphasized the importance of early detection in colorectal cancer. Catching the disease in its early stages not only increases the chances of survival but also reduces the potential for long-term side effects from treatments.

The studies published in the Journal of the American Medical Association highlight the success of the new screening guidelines in increasing early-stage diagnoses among the 45 to 49 age group. The rate of screening in this age group sharply increased after the recommendation change in 2021, leading to more cases of localized colorectal cancer being detected.

One of the key factors contributing to the rise in screening rates was the Affordable Care Act, which mandates private insurers to cover preventive services recommended by the USPSTF at no cost to the individual. This eliminated financial barriers for many individuals in the 45 to 49 age group, making it easier for them to access colorectal cancer screenings.

However, concerns remain about the potential impact of upcoming Medicaid cuts on access to screening for colorectal cancer. If individuals lose their health insurance coverage due to policy changes, it could affect their ability to undergo screening tests and receive timely medical care.

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Overall, the findings from these studies provide reassurance that lowering the age for colorectal cancer screening is effective in identifying cases of the disease at earlier stages. The success of the new guidelines underscores the importance of regular screening for colorectal cancer, even in younger age groups, to improve outcomes and save lives. Lowering the screening age by five years had a significant impact on the number of Americans who were now considered overdue for colorectal cancer screening. Approximately 20 million individuals between the ages of 45 and 49 suddenly found themselves in need of screening, presenting a challenge for healthcare providers to ensure that these individuals were promptly screened for colorectal cancer. UCLA’s May recognized the urgency of the situation and set out to find effective and efficient ways to facilitate screening for this new age group without overwhelming the healthcare system.

To address this issue, researchers conducted a study to evaluate the effectiveness of different strategies in increasing screening participation among adults aged 45 to 49. Four different approaches were tested, including opting in for colonoscopy, opting in for fecal testing, giving participants a choice between the two options, and mailing fecal tests directly to patients without asking. The results showed that the strategy of mailing fecal tests directly to patients was the most effective, with a screening rate of over 26% compared to 15% to 17% for the other interventions.

The success of the mailed test intervention provides valuable insights for healthcare systems looking to improve colorectal cancer screening rates in the 45 to 49 age group. Rather than developing new interventions, the focus should be on scaling up and implementing proven strategies like the mailed test approach. Julie Gralow, the chief medical officer for the American Society of Clinical Oncology, suggested enhancing the mailed test completion rate by providing patients with additional information about colorectal cancer, potentially through the use of artificial intelligence health navigators. A study conducted at Montefiore Einstein demonstrated that an AI tool significantly increased colonoscopy completion rates among patients who were already scheduled for the procedure.

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The findings from these studies underscore the significant impact that USPSTF recommendations can have on public health outcomes. UCLA’s May emphasized the importance of evidence-based guidelines grounded in public health theory and methods. By recognizing the power of guidelines and implementing effective strategies, healthcare providers can improve screening rates for colorectal cancer and other preventable diseases, ultimately leading to better health outcomes for the nation.

TAGGED:cancerChangeColonguidelineLivesSavedScreeningstudies
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