Using portable high-efficiency particulate air (HEPA) purifiers at home has been shown to have a significant impact on lowering systolic blood pressure (SBP) in adults with elevated baseline readings, even in areas with relatively low overall air pollution levels. This groundbreaking study, published in the Journal of the American College of Cardiology, sheds light on the importance of indoor air quality in maintaining heart health.
Particulate matter (PM) is a major contributor to air pollution and is closely linked to cardiovascular disease (CVD). Individuals living near high-traffic roadways are particularly vulnerable to elevated levels of PM from vehicle emissions, tire wear, and brake dust. These fine particles can infiltrate homes and pose a serious health risk, increasing the likelihood of hypertension and elevated blood pressure ā both significant risk factors for CVD.
Lead author of the study, Douglas Brugge, Ph.D., M.S., emphasizes the importance of addressing high blood pressure as a modifiable risk factor for cardiovascular disease. The research highlights the potential benefits of simple interventions, such as in-home air filtration, in improving heart health for at-risk individuals.
In a randomized crossover trial involving 154 adults living near highways, participants were assigned to receive either HEPA or sham filtration in their homes for one month, followed by a washout period with no filtration, and then the alternate treatment. Blood pressure measurements and participant questionnaires were collected at the start and end of each period.
The results revealed that participants with elevated SBP experienced a significant reduction in SBP after one month of HEPA filtration, compared to a slight increase during the sham filtration period. This difference of 3.0 mmHg in favor of HEPA filtration underscores the potential impact of indoor air quality on blood pressure regulation.
Jonathan Newman, M.D, M.P.H., stresses the harmful health effects of PM2.5 exposure, even at levels below current U.S. standards. As healthcare professionals, it is crucial to educate the public and advocate for policies that promote clean air and improve the overall health of the population.
Harlan M. Krumholz, M.D., S.M., Editor-in-Chief of JACC, acknowledges the study’s implications for cardiovascular health, suggesting that even minor improvements in indoor air quality can have a meaningful impact on blood pressure management for individuals at risk. While further research is needed to validate these findings, the study signals a promising avenue for enhancing heart health through indoor air quality interventions.
It is important to note the limitations of the study, including the homogeneous participant pool, exclusion of individuals on blood pressure medications, potential variations in purifier use, and the lack of data during warmer months or periods of higher indoor pollution.
In conclusion, the study underscores the potential benefits of HEPA air purifiers in reducing blood pressure and improving heart health, especially for individuals exposed to traffic pollution. By prioritizing indoor air quality and implementing simple interventions, we can work towards safeguarding cardiovascular health and reducing the burden of heart disease. For more information, refer to the study published in the Journal of the American College of Cardiology (2025).
This article was originally published by the American College of Cardiology. For more updates and information, visit their website at http://www.acc.org.
