Friday, 31 Oct 2025
  • Contact
  • Privacy Policy
  • Terms & Conditions
  • DMCA
logo logo
  • World
  • Politics
  • Crime
  • Economy
  • Tech & Science
  • Sports
  • Entertainment
  • More
    • Education
    • Celebrities
    • Culture and Arts
    • Environment
    • Health and Wellness
    • Lifestyle
  • 🔥
  • Trump
  • VIDEO
  • House
  • White
  • ScienceAlert
  • Trumps
  • Watch
  • man
  • Health
  • Season
Font ResizerAa
American FocusAmerican Focus
Search
  • World
  • Politics
  • Crime
  • Economy
  • Tech & Science
  • Sports
  • Entertainment
  • More
    • Education
    • Celebrities
    • Culture and Arts
    • Environment
    • Health and Wellness
    • Lifestyle
Follow US
© 2024 americanfocus.online – All Rights Reserved.
American Focus > Blog > Tech and Science > AI Creates New Glowing Protein, Simulating 500 Million Years of Evolution : ScienceAlert
Tech and Science

AI Creates New Glowing Protein, Simulating 500 Million Years of Evolution : ScienceAlert

Last updated: January 31, 2025 1:35 pm
Share
SHARE

Synthesizing New Proteins: AI Model Creates Custom Proteins Beyond Nature

The field of synthesizing new proteins, the building blocks of biological life, is experiencing a revolution with the development of a groundbreaking AI model. This new model promises to provide instructions for creating proteins that go far beyond what is naturally found in living organisms.

Recently, scientists in the US utilized EvolutionaryScale Model 3 (ESM3) to design a novel protein named esmGFP (green fluorescent protein). This protein only shares 58 percent of its composition with its closest natural relative, tagRFP.

According to the research team, this is equivalent to 500 million years of evolution processed by AI. This breakthrough opens up possibilities for designing custom-made proteins tailored for specific applications and unlocking new functionalities from existing proteins.

Protein AI model
ESM3 uses AI algorithms to construct new proteins from its training data. (EvolutionaryScale)

The researchers, led by Thomas Hayes, founder of EvolutionaryScale in New York, explained in their paper that more than three billion years of evolution have shaped the biological image encoded in natural proteins. They demonstrated that language models trained on evolutionary data can generate functional proteins that are vastly different from known proteins.

I’m so excited to share what we’ve been working on @EvoscaleAI. ESM3 is a multimodal generative masked language model for programming biology. Here’s a short thread on the architecture behind ESM3. 🧵https://t.co/jldHYRAPNy

— Thomas Hayes (@THayes427) June 25, 2024

ESM3 was trained on an extensive dataset comprising 3.15 billion protein sequences, 236 million protein structures, and 539 million protein annotations. By analyzing patterns in this vast data, the AI model can discern effective protein building strategies and functions.

See also  A Beginner’s Guide to Ethical and Sustainable Fashion

What sets esmGFP apart is its functionality – it fluoresces like tagRFP. Fluorescent proteins play a crucial role in various applications, including as markers in medicine and biotechnology, and even giving certain ocean organisms their luminescence.

AI Model Creates New Protein That Simulates 500 Million Years of Biological Evolution
A rendering of esmGFP, a new green fluorescent protein generated by ESM3 that is distant from other fluorescent proteins found in nature. (EvolutionaryScale)

The AI model streamlines the process of protein synthesis by minimizing trial and error while enabling exploration of uncharted territories in protein design.

The researchers emphasized that proteins exist within an organized space where each protein is connected to every other protein through potential evolutionary pathways. ESM3’s design is based on recognizing proteins in this space.

While proteins designed by ESM3 require validation, synthesis, and testing, the team is optimistic about further advancements in this field. In the near future, we could witness the production of proteins for a wide range of applications, from medicines to biomaterials, with the assistance of sophisticated AI algorithms.

The researchers explained that protein language models construct a model of the myriad potential evolutionary paths that could have been followed, rather than working within the physical constraints of evolution.

This groundbreaking research has been published in Science.

TAGGED:createsEvolutionglowingMillionproteinScienceAlertSimulatingYears
Share This Article
Twitter Email Copy Link Print
Previous Article Ernesto Neto Crochets an Enormous Snake to Slither Inside Le Bon Marché — Colossal
Next Article How to Start an Office Recycling Program
Leave a comment

Leave a Reply Cancel reply

Your email address will not be published. Required fields are marked *

Popular Posts

Gut Bacteria Found to Soak Up Toxic Forever Chemicals : ScienceAlert

Could Gut Bacteria Help Protect Us From 'Forever Chemicals'? Perfluoroalkyl and polyfluoroalkyl substances (PFAS) are…

July 3, 2025

Why Trump’s Claims About Americans Splitting The Atom Angers New Zealanders

Washington: Picture a newly-elected leader of a nation laying claim to the legacy of a…

January 22, 2025

Active US airman accused of killing woman, 21, on his South Dakota military base: authorities

An Active Air Force Member Arrested for Alleged Murder on South Dakota Military Base An…

March 17, 2025

Biohackers think you can program the body like a computer. They’re wrong

The rise of biohacking and longevity seekers in recent years has brought about a wave…

May 27, 2025

Canada coach Jesse Marsch suspended two games for antics in Concacaf Nations League win over USMNT

Getty Images After his conduct at the Concacaf Nations League finals in March, Canada head…

April 17, 2025

You Might Also Like

Nanotyrannus Isn’t a Juvenile T-Rex—It’s a Separate Dinosaur
Tech and Science

Nanotyrannus Isn’t a Juvenile T-Rex—It’s a Separate Dinosaur

October 31, 2025
How Much Does Grocery Delivery App Development Cost in 2025?
Tech and Science

How Much Does Grocery Delivery App Development Cost in 2025?

October 31, 2025
Boy’s body was mummified and turned green by a copper coffin
Tech and Science

Boy’s body was mummified and turned green by a copper coffin

October 31, 2025
Bevel raises M Series A from General Catalyst for its AI health companion
Tech and Science

Bevel raises $10M Series A from General Catalyst for its AI health companion

October 31, 2025
logo logo
Facebook Twitter Youtube

About US


Explore global affairs, political insights, and linguistic origins. Stay informed with our comprehensive coverage of world news, politics, and Lifestyle.

Top Categories
  • Crime
  • Environment
  • Sports
  • Tech and Science
Usefull Links
  • Contact
  • Privacy Policy
  • Terms & Conditions
  • DMCA

© 2024 americanfocus.online –  All Rights Reserved.

Welcome Back!

Sign in to your account

Lost your password?