By BRUCE SCHREINER and HALLIE GOLDEN, Associated Press
LOUISVILLE, Ky. (AP) — A UPS cargo plane crashed and exploded in a massive fireball Tuesday while taking off from the company’s global aviation hub in Louisville, Kentucky, killing at least three people and injuring 11 — numbers that were likely to grow, the state’s governor said.
The plane crashed about 5:15 p.m. as it was departing for Honolulu from UPS Worldport at Louisville Muhammad Ali International Airport.
“Right now we believe we have at least three fatalities, though I believe that number is going to get larger. We have at least 11 injuries, some of them very significant,” Gov. Andy Beshear said.
Video showed flames on the plane’s left wing and a trail of smoke. The plane then lifted slightly off the ground before crashing and exploding in a huge fireball. Video also revealed portions of a building’s shredded roof next to the end of the runway.
“Anybody who has seen the images, the video, knows how violent this crash is,” Beshear said.
He said he didn’t know the status of the three crew members aboard the plane, a McDonnell Douglas MD-11 made in 1991.
UPS’s largest package handling facility is in Louisville. The hub employs thousands of workers, has 300 daily flights and sorts more than 400,000 packages an hour.
“We all know somebody who works at UPS,” Louisville Metro Council member Betsy Ruhe said. “And they’re all texting their friends, their family, trying to make sure everyone is safe. Sadly, some of those texts are probably going to go unanswered. My heart goes out to those families and those friends.”
UPS acknowledged the crash in a brief statement and said the National Transportation Safety Board would handle the investigation.
The airport, meanwhile, was shut down and wasn’t expected to resume operations until Wednesday morning.
“We don’t know how long it’s going to take to render that scene safe,” said Louisville Police Chief Paul Humphrey.
The governor said a business, Kentucky Petroleum Recycling, appeared to be “hit pretty directly,” and a nearby auto parts operation was also affected.
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This photo provided by Brad Harvey shows thick, black smoke rising after reports of a plane crash near Louisville International Airport, Tuesday, Nov. 4, 2025, in Louisville, Ky. (Brad Harvey via AP)
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This photo provided by Brad Harvey shows thick, black smoke rising after reports of a plane crash near Louisville International Airport, Tuesday, Nov. 4, 2025, in Louisville, Ky. (Brad Harvey via AP)
A video taken by Leirim RodrĂguez shows several massive balls of flames exploding into the sky in a row, followed by large billowing clouds of black smoke. Rodriguez told the AP she and her husband just happened to be in the area at the time of the explosion.
Tom Brooks Jr., who runs a metal recycling business down the street, said the unbelievable magnitude of the crash “just rocked the whole place.”
“This was massive. I mean, it literally looked like a war zone,” he said.
Destyn Mitchell said she was working as a host at an Outback restaurant, about a 15-minute drive from the crash, when she heard a loud boom. About 20 people were in the restaurant.
“The mood in the restaurant was very shaken up,” Mitchell said. “Everyone is really concerned.
Shelter-in-Place Order Extended to Areas North of Louisville Airport
People who recently sat down for a meal quickly gathered their belongings and left within half an hour, eager to return home.
The shelter-in-place directive now includes all regions located north of the Louisville airport, stretching up to the Ohio River. Situated just a short 10-minute drive from downtown Louisville, the airport is close to the river, which marks the border with Indiana. This area boasts residential neighborhoods, a water park, and various museums.
Reporting by Golden in Seattle. Additional contributions by AP journalists Ed White in Detroit, John Raby in Cross Lanes, West Virginia, and Adrian Sainz in Memphis, Tennessee.
