Colorectal cancer, once considered a disease of old age, has now become the leading cause of cancer-related deaths among young people in the United States. A new report from the American Cancer Society has revealed that while most types of cancer have become less deadly over time in adults younger than 50, colon and rectum cancers continue to claim lives at alarming rates.
The report analyzed data from 1990 to 2023, showing a 44 percent decrease in overall cancer mortality in the under-50 age group. However, colorectal cancer has seen a steady increase in mortality rates, jumping from the fifth leading cause of cancer deaths in 1990 to the first in 2023.
William Dahut, chief scientific officer at the American Cancer Society, describes this shift as an “inflection point,” marking the first time colorectal cancer has topped the list of cancer-related deaths in individuals under 50.
While advancements in therapies have led to a decline in deaths from other leading cancers such as breast, lung, and pancreatic cancers, colorectal cancer mortality rates have worsened. Jeff Meyerhardt, a gastrointestinal oncologist, notes that many of the cancers in the study are typically seen in older individuals, making the rise of colorectal cancer among younger age groups particularly concerning.
One factor contributing to the high mortality rates is late-stage diagnosis, with the majority of cases being detected at advanced stages when treatment options are limited. Andrea Cercek, founder of the Center for Young Onset Colorectal and Gastrointestinal Cancer, emphasizes the importance of early detection and screening for colorectal cancer, especially in individuals under 50.
Researchers are investigating various factors that may be driving the trend, including diet, exercise, genetics, and environmental influences. Identifying credible risk factors will be essential in developing targeted screening strategies for high-risk individuals without subjecting them to unnecessary procedures.
As the number of younger people diagnosed with colorectal cancer continues to rise, improving therapies and providing support during recovery will be crucial. The alarming increase in colorectal cancer cases among young adults underscores the need for continued research and efforts to combat this deadly disease.
Survivorship Challenges for Young Adults with Colorectal Cancer
Surviving colorectal cancer as a young adult is a life-changing experience that can have a significant impact on emotional, physical, and financial well-being. According to Dr. Smith, an oncologist specializing in colorectal cancer, it is crucial to acknowledge the challenges that young adults face during survivorship.
The journey of survivorship for young adults with colorectal cancer is incredibly difficult and can be taxing in many ways. Emotional challenges such as anxiety, depression, and fear of recurrence are common among survivors. The physical toll of treatment, including surgery, chemotherapy, and radiation, can lead to long-term side effects that impact daily life. Additionally, the financial burden of medical bills and lost income can add to the stress of survivorship.
Early diagnosis is key to improving outcomes for young adults with colorectal cancer. Dr. Smith emphasizes the importance of early detection in providing the best possible care for patients. Timely diagnosis can lead to more effective treatment options and a higher chance of survival.
As advancements in treatment and detection continue to evolve, there is hope that colorectal cancer survival rates will improve and eventually be on par with other types of cancer. Research efforts are focused on developing targeted therapies, immunotherapy, and precision medicine to tailor treatment plans to individual patients.
Overall, survivorship for young adults with colorectal cancer is a complex and challenging journey. By raising awareness, promoting early detection, and supporting research efforts, we can improve outcomes and quality of life for survivors.

