Colossal Biosciences scientist Beth Shapiro holds a portion of a woolly mammoth tusk recovered from the Arctic.
Rob Stein/NPR
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Rob Stein/NPR
Imagine stepping into a world where extinct species like the woolly mammoth, Tasmanian tiger, and dodo bird could be brought back to life. This is the ambitious goal of Colossal Biosciences Inc., a groundbreaking de-extinction and conservation company based in Dallas.
Despite facing both enthusiasm and skepticism, Colossal is dedicated to utilizing cutting-edge technologies to resurrect ancient species and potentially save endangered animals. As NPR gains exclusive access to Colossal’s state-of-the-art 55,000-square foot lab, a deeper understanding of their groundbreaking work emerges.
From extracting ancient DNA to creating gene-edited mammoth embryos, Colossal’s team of over 260 scientists is at the forefront of genetic research. The company’s innovative approach involves analyzing mammoth DNA samples, comparing them to living elephants, and ultimately attempting to birth a mammoth clone within the next two years.
Exploring New Horizons
As NPR delves further into Colossal’s lab, the unveiling of genetically engineered woolly mice showcases a pivotal step in the company’s mission. These mice, modified to resemble woolly mammoths, highlight the successful editing of specific genes responsible for distinctive traits.
Additionally, Colossal made headlines with the recreation of the dire wolf, a species reminiscent of creatures from the popular series Game of Thrones. While critics question the authenticity of these revived species, Colossal remains steadfast in its commitment to genetic restoration.
Debates surrounding the ethics of resurrecting extinct species come to the forefront, with concerns about the well-being and sustainability of these recreated animals. Despite the ongoing discourse, Colossal’s innovative technologies hold promise for not only reviving lost species but also advancing conservation efforts for existing wildlife.
With a focus on leveraging synthetic biology for conservation, Colossal’s groundbreaking initiatives extend beyond de-extinction. By establishing the Colossal Foundation and collaborating with global partners, the company aims to preserve biodiversity and champion the future of life on Earth.
“Our work is a testament to undoing past mistakes and embracing the boundless potential of genetic restoration,” says Ben Lamm, CEO and co-founder of Colossal. “It’s not just about bringing back extinct species, but about utilizing technology to ensure a sustainable future for all living creatures.”
