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American Focus > Blog > Health and Wellness > Ebola outbreak in Central Africa could reach 20,000 cases
Health and Wellness

Ebola outbreak in Central Africa could reach 20,000 cases

Last updated: June 5, 2026 9:45 pm
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Ebola outbreak in Central Africa could reach 20,000 cases
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NEW YORK — The Ebola outbreak in Central Africa has the potential to escalate to 20,000 cases or more, contingent on the speed of isolating infected individuals to curb the spread, according to a recent analysis by U.S. health authorities.

The Centers for Disease Control and Prevention (CDC) released computer model-generated scenarios on Friday, projecting outcomes ranging from 10,000 to over 20,000 cases. If these projections are accurate, the worst-case scenario could rival the most severe Ebola outbreak in history, the West Africa epidemic from 2014-2016, which saw more than 28,000 reported cases and over 11,000 fatalities.

“The modeling indicates that without strong public health measures, an outbreak of this magnitude is conceivable,” stated Satish Pillai, the incident manager for the CDC’s Ebola response, during a press briefing.

Jennifer Nuzzo, the director of Brown University’s Pandemic Center, remarked that the modeling “confirms our initial concerns: This outbreak is on a perilous path” unless more efforts are made to halt Ebola’s spread.

However, she advised caution in interpreting the specific numbers, emphasizing that predicting outbreak progression can be exceedingly challenging. “It’s difficult to make precise projections with limited data,” she noted.

STAT Plus: As Ebola outbreak in Central Africa grows, the U.S. turns itself into a fortress

The Africa Centers for Disease Control and Prevention reported on Friday approximately 400 confirmed cases, including 63 deaths. Experts suggest there may be additional cases undiagnosed or unreported.

Ebola viruses are transmitted through contact with bodily fluids such as vomit, blood, and semen. There are no specific treatments or vaccines for the Bundibugyo virus, the strain behind the current outbreak, which often proves fatal.

The World Health Organization declared the outbreak a global health emergency in May. Some experts believe infections began as early as February, though health officials initially tested for a different Ebola strain.

The response to the outbreak has been complicated by armed conflict between Congo’s government and the Rwanda-supported M23 rebel group, along with attacks by the Islamic State-affiliated Allied Democratic Force. This violence has led to significant displacement in the conflict zones, according to officials.

Earlier this week, Nuzzo assessed the risk to the United States as low. “I don’t anticipate it will reach here and spread widely,” she told reporters. The CDC echoed this view in a paper released Friday.

This outlook is partly due to U.S. government measures that restrict entry to individuals without U.S. passports and U.S. green-card holders who have visited Congo, Uganda, or South Sudan within the previous 21 days. Additionally, U.S. citizens returning from these countries are being subjected to health screenings and directed to four designated airports.

The CDC’s modeling report outlines potential scenarios based on various factors, such as the number of infections and deaths to date, and the success rate of identifying and isolating infected individuals before further spread occurs.

If approximately 50 deaths had occurred and 20% of infected individuals were isolated by late May, most simulations predict at least 20,000 cases and 4,000 deaths in Africa over three months.

Pillai mentioned that the actual isolation rate is uncertain but is thought to be “on the lower end of the scenarios” modeled by the CDC.

If isolation rates improve to 50% or 70%, the number of cases could decrease to around 10,000, according to CDC officials. However, if the number of deaths was underestimated in late May, the situation could worsen, they added.

During the significant Ebola outbreak in West Africa, some CDC models proved to be inaccurate. In 2014, the CDC estimated that, without intervention, up to 1.4 million people could be infected, a figure that was over 50 times the actual outcome.

___

The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Department of Science Education and the Robert Wood Johnson Foundation. The AP is solely responsible for all content.

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