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American Focus > Blog > Tech and Science > Experiment Reveals What Prolonged Fasting Actually Does to The Human Body : ScienceAlert
Tech and Science

Experiment Reveals What Prolonged Fasting Actually Does to The Human Body : ScienceAlert

Last updated: June 8, 2025 7:45 am
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Experiment Reveals What Prolonged Fasting Actually Does to The Human Body : ScienceAlert
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Are Water-Only Fasting Diets Safe? What the Research Says

With recommendations for water-only fasting diets flooding social media feeds, it’s important to consider the potential negative impacts before diving in. Researchers have recently conducted a study on the effects of prolonged water-only fasting diets on the body, highlighting some concerning findings.

The study, which involved 20 participants undergoing a 10-day water-only fasting regimen, revealed both positive and negative outcomes. While the participants experienced an average weight loss of 7.7 percent, they also reported side effects such as headaches, insomnia, and low blood pressure. Additionally, the fasting seemed to increase inflammation in the body, putting extra stress on the participants’ systems.

Key Findings from the Study

One of the main ways researchers measured the effects of fasting was through analyzing protein levels in the participants’ blood plasma. They found that various pro-inflammatory proteins, including C-reactive protein (CRP) and interleukin 8 (IL-8), became more abundant during the fasting period.

Furthermore, the study highlighted a decrease in proteins associated with muscle and bone breakdown, as well as amyloid beta proteins linked to Alzheimer’s disease development.

It’s important to note that these findings are preliminary and based on a small sample size of overweight individuals. The effects of water-only fasting may vary in larger populations or individuals with different body compositions.

Seeking Medical Advice Before Starting a Fasting Diet

Given the potential risks associated with prolonged fasting, it’s crucial to consult with a healthcare professional before embarking on such a diet. The study’s lead researcher emphasized the need for a better understanding of the long-term implications of fasting on diverse populations.

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While intermittent fasting has shown some potential benefits in previous studies, including cell aging slowdown and inflammation reduction, the impact of prolonged fasting remains a topic of ongoing research.

Ultimately, there’s no one-size-fits-all approach to fasting, and any weight loss strategy involving fasting should be carefully managed and monitored by medical professionals.

As more research is conducted on the effects of fasting on the body, it’s essential to prioritize health and safety when considering extreme dietary measures.

For more information, you can access the full research paper published in Molecular Metabolism.

TAGGED:bodyExperimentfastinghumanProlongedRevealsScienceAlert
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