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American Focus > Blog > Tech and Science > Gene-edited cells that evade rejection show promise in type 1 diabetes
Tech and Science

Gene-edited cells that evade rejection show promise in type 1 diabetes

Last updated: January 11, 2025 11:31 pm
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Gene-edited cells that evade rejection show promise in type 1 diabetes
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First Human Trial of Gene-Edited Insulin-Producing Cells Shows Promise

A transmission electron micrograph of a section through pancreas tissue, showing cells that produce insulin

STEVE GSCHMEISSNER/SCIENCE PHOTO LIBRARY/Alamy

The first human trial of insulin-producing cells that have been gene-edited to evade immune attack is showing promising results. A 42-year-old man with type 1 diabetes received an injection of these modified cells in early December, and they have successfully survived and produced insulin for a month.

As a precautionary measure, only a small number of insulin-producing beta cells were injected into the man’s forearm muscle during this initial trial. Therefore, he still requires insulin injections as part of his diabetes management. The long-term efficacy and safety of this gene-editing approach are yet to be determined, and further research is needed to assess the full potential of this innovative treatment.

See also  People under 40 diagnosed with type 2 diabetes have mortality rate four times higher than general population: Study
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