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American Focus > Blog > Tech and Science > Is The Y Chromosome Vanishing? A New Sex Gene May Be The Future of Men : ScienceAlert
Tech and Science

Is The Y Chromosome Vanishing? A New Sex Gene May Be The Future of Men : ScienceAlert

Last updated: December 6, 2025 4:15 am
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Is The Y Chromosome Vanishing? A New Sex Gene May Be The Future of Men : ScienceAlert
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The Future of the Y Chromosome: Is It Doomed or Here to Stay?

In a groundbreaking study back in 2002, evolutionary biologist Jenny Graves made a controversial calculation that sent shockwaves through the scientific community. Graves predicted that the human Y chromosome, responsible for male sex determination, was on a path to extinction. With 97 percent of its ancestral genes lost over the last 300 million years, the Y chromosome’s demise seemed inevitable. If this trend continued, Graves speculated that it could disappear within a few million more years.

However, the media frenzy that followed Graves’ calculation often sensationalized the implications, leading to misconceptions about the fate of males and the human species as a whole. Graves herself clarified that her calculation was a rough estimate and not a prophecy of male extinction.

Genetic Inheritance Humans
Typical genetic inheritance in humans. (ttsz/Getty Images)

While the potential disappearance of the Y chromosome raises questions about the future of male sex determination, evidence from other mammals, fish, and amphibians suggests that such genetic shifts are not unprecedented. Some species have completely lost their Y chromosomes, with sex-determining genes moving to other chromosomes without threatening reproduction.

Despite differing interpretations among evolutionary biologists like Jenn Hughes and Jenny Graves, recent studies have highlighted the conservation of core Y genes in primates, challenging the notion of a steady decline in Y chromosome integrity. While Hughes believes in the long-term stability of the Y chromosome, Graves remains skeptical, citing the ongoing evolution and gene loss on the Y chromosome.

Y Chromosome Repair
How a Y chromosome repairs itself without a second copy, as there are with two X chromosomes. (Silber, Middle East Fertility Society Journal, 2011)

As the debate on the fate of the Y chromosome continues, the scientific community remains divided on whether it is destined for extinction or will persist through evolutionary mechanisms. While Graves acknowledges the potential for stabilization at certain points, she emphasizes the slow and unpredictable nature of genetic evolution.

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Ultimately, the future of the Y chromosome remains uncertain, with researchers like Hughes and Graves offering contrasting perspectives on its longevity and significance in the evolutionary timeline. Whether the Y chromosome is a relic of the past or a resilient survivor of genetic change, its story continues to captivate scientists and the public alike.

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TAGGED:ChromosomeFuturegeneMenScienceAlertSexvanishing
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