The University of Cincinnati engineers have developed a groundbreaking device to aid doctors in diagnosing depression and anxiety. The device, known as a “lab-on-a-chip,” is designed to measure the stress hormone cortisol from a patient’s saliva. This innovative approach can provide valuable diagnostic information even if patients do not express feelings of anxiety, stress, or depression through standard mental health questionnaires.
Mental health disorders impact millions of people globally, with stress disorders like anxiety and depression ranking among the leading causes of disability. Elevated cortisol levels have been linked to various mental health conditions, including depression and anxiety. The lab-on-a-chip system created by UC researchers allows for the real-time tracking of a patient’s cortisol levels. The system includes a disposable collection device that is placed in the mouth and then inserted into a reader. Within minutes, the reader can transmit results to a portable analyzer and smartphone.
The study detailing this innovative device was published in the journal Biomedical Microdevices. The goal of this technology is to enable point-of-care testing, allowing patients to conduct tests at home or in a clinic. By providing quick and accurate results, doctors can make timely interventions in mental health care.
The device combines traditional psychometric evaluations with physiological biomarker measurements to offer evidence-based diagnostics for stress disorders. Patients can easily perform the tests themselves and share the results with healthcare providers via smartphones.
In addition to diagnosing stress disorders, the device can be adapted for other health issues. For instance, the researchers explored the use of the device to measure troponin, a protein released into the bloodstream during heart damage, such as a heart attack. By monitoring troponin levels in the blood, clinicians can quickly assess a patient’s condition and provide immediate care when necessary.
Moreover, the UC researchers have also developed a point-of-care testing platform for COVID-19, showcasing the versatility and potential applications of their innovative technology. This new design was unveiled in the journal Sensors and Diagnostics.
Overall, the development of these lab-on-a-chip devices represents a significant advancement in healthcare technology. By providing quick and accurate diagnostics for stress disorders, heart issues, and infectious diseases like COVID-19, these devices have the potential to revolutionize the way medical conditions are diagnosed and treated. The researchers are optimistic about the future applications of their technology and are eager to collaborate with healthcare professionals to further validate its effectiveness through clinical trials.
