New Mexico has long been on alert for hantavirus, ever since a deadly outbreak in 1993 revealed the presence of the virus in North America. Typically spread by deer mice, the virus can cause severe cardiopulmonary symptoms in humans, with a mortality rate of about 35%. However, recent research conducted by University of New Mexico scientists has uncovered that more than 30 species of rodents and small mammals in the Southwest actually carry the hantavirus, including ground squirrels, chipmunks, gophers, rats, and even house mice.
In a study published in PLOS Pathogens, researchers led by Dr. Steven Bradfute found genomic material from the sin nombre virus in a quarter of the small mammals collected in New Mexico between 2019 and 2023. This discovery suggests that multiple species can potentially spread the virus through aerosolized droppings. The team was able to isolate live hantavirus from the salivary glands and lung tissue of these animals, indicating their potential as vectors for the disease.
One key question that remains unanswered is why reported human hantavirus cases are concentrated in the Four Corners region of New Mexico, despite the widespread presence of the virus in different mammal species across the state. Possible explanations include variations in the genetic sequence of the virus, differences in viral transmission efficiency, or higher viral loads in specific regions.
The recent death of Betsy Arakawa, wife of actor Gene Hackman, due to hantavirus in their Santa Fe home serves as a tragic reminder of the importance of taking precautions. Symptoms of hantavirus infection can mimic the flu or COVID-19 initially, but can progress to severe respiratory distress and exhaustion. With no effective antiviral drugs available, treatment focuses on managing symptoms and supporting patients through ECMO machines.
Prevention is key when it comes to hantavirus, as the virus is not transmitted between humans and does not survive long in open air or sunlight. Individuals should take precautions when cleaning up rodent droppings, wearing masks and gloves, and avoiding activities that generate aerosols. While the risk of transmission is relatively low, vigilance is essential in areas where hantavirus is prevalent.
Overall, the research conducted by the University of New Mexico sheds light on the diverse range of small mammals that can carry hantavirus and underscores the importance of awareness and prevention measures in regions where the virus is present. By understanding the potential vectors of the disease and taking appropriate precautions, individuals can reduce the risk of hantavirus infection and protect their health.