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American Focus > Blog > Health and Wellness > Managing The Rarest, Sickest, And Most Expensive Patients
Health and Wellness

Managing The Rarest, Sickest, And Most Expensive Patients

Last updated: November 3, 2025 6:55 pm
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Managing The Rarest, Sickest, And Most Expensive Patients
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Value-Based Care: A New Direction Towards Better Managing Our Sickest Patients

Value-based care has been a cornerstone of healthcare for the past two decades, with the premise that better managing the sickest patients will ultimately lead to lower costs of care. This idea has sparked numerous disease-management programs, care-coordination models, and technological innovations. However, as the field has evolved, a glaring reality has surfaced – much of value-based care has not been directed towards the sickest patients.

Instead, the focus has primarily been on high-volume, moderately expensive chronic diseases such as congestive heart failure, diabetes, and chronic obstructive pulmonary disease. While these efforts have brought about incremental improvements, they have overlooked a small subset of patients with ultra-high acuity, ultra-high-cost conditions that defy conventional expectations. These patients, suffering from conditions like ALS, advanced muscular dystrophy, or complex transplantation scenarios, represent a minute fraction of the total patient population but drive a disproportionate amount of medical expense and hardship.

The traditional approach to value-based care has gravitated towards large-scale, predictable conditions for practical reasons. Managing tens of thousands of patients with conditions like diabetes offers a tangible return on investment, as clinical guidelines provide clear pathways for care that can be easily scaled. However, this approach has left patients with catastrophic, idiosyncratic diseases largely underserved by innovation.

The case for a new frontier in value-based care is compelling. By focusing on patients with ultra-high acuity conditions who require frequent hospitalizations, healthcare systems have the potential to realize significant cost savings. Implementing intensive, protocolized outpatient care driven by clinical expertise could prevent unnecessary hospitalizations and reduce overall healthcare expenses.

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With healthcare affordability becoming increasingly challenging, health plans and provider organizations are seeking new strategies to lower costs. The next phase of value-based care demands new clinical operating systems, specialized multidisciplinary models, redesigned payment structures, and advanced analytics to cater to the unique needs of the sickest patients.

In order to truly fulfill the promise of value-based care, the focus must shift towards building models that support the individuals who consume a disproportionate amount of healthcare resources. These patients deserve a care model that acknowledges the complexity of their conditions and provides them with the support they need to navigate their illnesses with dignity.

As we look towards the future of value-based care, it is imperative that we prioritize the needs of the truly sickest patients. By following the money and the humanity to where the suffering is greatest, we can usher in a new era of healthcare that is truly patient-centered and cost-effective.

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