Research Shows Broken Heart Syndrome Can Be Fatal
We’ve all felt the emotional pain of a broken heart, but did you know that it can also have physical consequences? Takotsubo cardiomyopathy (TC), also known as “broken heart syndrome,” is a condition where the heart weakens due to extreme stress – whether physical or emotional. A recent study conducted by researchers at the University of Arizona examined data from nearly 200,000 patients in the US between 2016 and 2020.
The study revealed that the incidence of TC slightly increased over the study period for both men and women, with higher overall rates among females. Unfortunately, fatalities and complications from the condition were also relatively high, indicating a concerning trend in the US.
While TC was more prevalent in women, the study found that men were more than twice as likely to die from the condition, with a death rate of 11.2 percent for males compared to 5.5 percent for females. The overall death rate stood at 6.5 percent.
Interventional cardiologist M. Reza Movahed expressed surprise at the high mortality rate and in-hospital complications associated with TC. The researchers proposed a hypothesis for the gender disparity, suggesting that hormonal differences and the type of stress trigger (physical or emotional) could play a role in the outcomes.

Complications arising from TC included congestive heart failure, atrial fibrillation, cardiogenic shock, stroke, and cardiac arrest. These symptoms often mimic a heart attack, making accurate diagnosis and treatment crucial.
Despite being a known condition, there are still many unanswered questions surrounding TC. Researchers emphasize the importance of further study to improve treatment and reduce complications. While not every case of TC is linked to relationship issues, the impact of emotional stress on physical health, particularly the heart, cannot be ignored.
Movahed stressed the need for more research and innovative treatment approaches to address the alarming death rates associated with TC. The findings of this study have been published in the Journal of the American Heart Association.