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American Focus > Blog > Health and Wellness > Metals in the body from pollutants associated with progression of harmful plaque buildup in the arteries
Health and Wellness

Metals in the body from pollutants associated with progression of harmful plaque buildup in the arteries

Last updated: September 18, 2024 9:35 am
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Metals in the body from pollutants associated with progression of harmful plaque buildup in the arteries
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A new study conducted by Columbia University Mailman School of Public Health has found a significant association between metal exposure from environmental pollution and the buildup of calcium in the coronary arteries. This buildup is comparable to traditional risk factors like smoking and diabetes, indicating that metal exposure may play a crucial role in the progression of atherosclerosis – a condition affecting the cardiovascular system.

Atherosclerosis is a condition where the arteries become narrowed and hardened due to a buildup of plaque, leading to restricted blood flow and the formation of blood clots. This condition is a major underlying cause of heart attacks, strokes, and peripheral artery disease. The study, published in the Journal of the American College of Cardiology, highlights the importance of considering metal exposure as a significant risk factor for cardiovascular disease.

Lead author of the study, Katlyn E. McGraw, Ph.D., emphasized the potential implications of these findings for new prevention and treatment strategies targeting metal exposure. The researchers used data from the Multi-Ethnic Study of Atherosclerosis (MESA) to track urinary metal levels in a diverse population over a 10-year period. The study focused on both non-essential metals like cadmium, tungsten, and uranium, as well as essential metals like cobalt, copper, and zinc.

The results indicated that higher urinary levels of certain metals were associated with increased coronary calcification over the 10-year period. For instance, comparing the highest to the lowest quartile of urinary cadmium, tungsten, uranium, and cobalt, significant increases in coronary artery calcium levels were observed. These findings suggest that metal exposure may contribute to the progression of atherosclerosis and cardiovascular disease.

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Furthermore, the study revealed variations in urinary metal levels based on demographic characteristics such as age, ethnicity, education level, and geographic location. Participants with higher metal exposure levels were more likely to exhibit increased coronary calcification over time. The researchers underscored the need for heightened awareness and regulatory measures to limit metal exposure in order to protect cardiovascular health.

While the study has some limitations, such as potential confounding factors and variability in exposure sources, it provides valuable insights into the impact of metal exposure on cardiovascular health. The findings highlight the importance of addressing environmental pollutants like metals as a significant risk factor for atherosclerosis and cardiovascular disease.

In conclusion, this study sheds light on the role of metal exposure in the progression of atherosclerosis and emphasizes the need for further research and interventions to reduce metal exposure and protect cardiovascular health. The implications of these findings could lead to new strategies for preventing and managing atherosclerosis in at-risk populations.

TAGGED:arteriesbodybuildupharmfulMetalsplaquepollutantsprogression
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