Seizure control is a journey that requires time, patience, and persistence. A recent international study conducted across 34 epilepsy centers in the U.S., Australia, and Europe brings new hope for people with seizures, showing that most newly diagnosed patients can achieve lasting control of their seizures, even if their first medication doesn’t work.
The study, published in JAMA Neurology, followed nearly 450 people newly diagnosed with focal epilepsy, the most common form of the condition. While only about one in four became seizure-free on their first medication, more than half ultimately achieved control. For most patients, this journey to seizure control took 12 months or longer, emphasizing the importance of perseverance in finding the right treatment.
Dr. Manisha Holmes, a co-author of the study and an expert in epilepsy, highlights the significance of the findings for newly diagnosed patients. She emphasizes that seizure freedom is achievable for most individuals but may require time and persistence to find the optimal treatment.
The first year after an epilepsy diagnosis can be challenging, with patients facing physical risks, lifestyle disruptions, and emotional stress. It’s essential for healthcare providers to work closely with patients to determine the best treatment regimen tailored to their individual needs.
The study also underscores the importance of early follow-up and flexibility in adjusting treatment regimens. While the initial prescription may not always be the most effective, there are over 30 medications available to treat seizures, and physicians should consider the unique characteristics of each patient when selecting a treatment plan.
Specialist care and regular follow-up with a neurologist or epileptologist are crucial for newly diagnosed epilepsy patients. These specialists can conduct advanced testing, adjust medications, and explore alternative therapies to optimize treatment outcomes and improve quality of life.
In addition to medication, lifestyle and wellness practices play a significant role in seizure control and overall well-being. Patients can enhance brain resilience through activities such as maintaining consistent sleep schedules, managing stress, exercising regularly, and engaging in creative pursuits.
Technology and data analytics are transforming epilepsy care, with the potential to predict drug resistance and guide therapy decisions in real time. As advancements in precision medicine continue to evolve, it’s essential to prioritize equity in access to care and ensure that innovations benefit all populations, regardless of background or socioeconomic status.
Overall, the study highlights the importance of perseverance, collaboration with healthcare providers, and a holistic approach to epilepsy treatment. By working together and incorporating lifestyle and wellness practices, most people living with seizures can achieve meaningful control and regain their independence.

