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American Focus > Blog > Economy > Novo Nordisk shares plummet as 2025 guidance is cut, overshadowing new CEO
Economy

Novo Nordisk shares plummet as 2025 guidance is cut, overshadowing new CEO

Last updated: July 30, 2025 5:05 am
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Novo Nordisk shares plummet as 2025 guidance is cut, overshadowing new CEO
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Novo Nordisk, a major player in the pharmaceutical industry, has recently faced setbacks that have led to a significant drop in its sales outlook for 2025. The company, known for its blockbuster drug Wegovy (semaglutide), lost a crucial court trial that would have protected its market share from competition. As a result, Novo Nordisk has revised its full-year sales growth forecast to be between 8% and 14%, a considerable decrease from its previous estimate of 13% to 21%.

The news of the slashed sales outlook caused investor concern, leading to a 21.7% drop in Novo Nordisk’s stock price. This decline wiped out over €60 billion ($69 billion) from the company’s market value. The stock’s performance overshadowed the announcement of Maziar Mike Doustdar taking over as the new CEO of the company, succeeding Lars Fruergaard Jørgensen, who left in May amid concerns about Novo Nordisk’s position in the weight loss market.

Doustdar, who has been with Novo Nordisk since 1992, faces the challenge of regaining the company’s leading position in the glucagon-like peptide 1 receptor agonists (GLP-1RA) market. Competitor Eli Lilly has been gaining ground with its drug tirzepatide, which has shown higher efficacy compared to semaglutide. This has resulted in Eli Lilly outpacing Novo Nordisk in sales growth, with a forecast for continued success in the obesity market.

Novo Nordisk attributed the downward revision in its sales outlook to lower-than-expected growth for Wegovy in the US obesity market and challenges with the diabetes drug Ozempic in the US GLP-1RA market. Additionally, the company cited difficulties in penetrating international markets with Wegovy. The rise of compounded semaglutide as a more affordable alternative has also contributed to Novo Nordisk’s declining market share.

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Despite these challenges, Novo Nordisk remains committed to its mission of delivering innovative treatments to patients. The company is making strategic changes, including merging early research and development activities and appointing new executives to key roles. Doustdar expressed his determination to lead Novo Nordisk to new heights and provide patients with the innovation they need.

The recent developments at Novo Nordisk highlight the competitive nature of the pharmaceutical industry and the importance of staying ahead in a rapidly evolving market. As the company navigates these challenges, investors and stakeholders will be closely watching its progress under new leadership.

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