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American Focus > Blog > Tech and Science > Pomegranates Could Limit Risks From Controversial Sports Supplement : ScienceAlert
Tech and Science

Pomegranates Could Limit Risks From Controversial Sports Supplement : ScienceAlert

Last updated: July 7, 2025 12:30 am
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Pomegranates Could Limit Risks From Controversial Sports Supplement : ScienceAlert
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Sport supplements are a common topic of discussion for those who regularly engage in exercise. Whether you’re a fan of these supplements or not, it’s hard to escape the conversations surrounding their benefits and risks. L-carnitine, in particular, is a supplement that has sparked controversy due to conflicting research findings.

Research has shown that l-carnitine can support muscle recovery and enhance exercise performance. However, there are also concerns that it may contribute to cardiovascular disease. A recent study conducted by a team of researchers found that consuming pomegranate alongside l-carnitine may help counteract the negative effects of the supplement.

L-carnitine is a compound that is naturally produced by the body in small amounts. It is also commonly found in meat and dairy products. While some manufacturers add l-carnitine to energy drinks and protein powders to enhance their value, the supplement itself is not inherently harmful. The risks associated with l-carnitine are attributed to the way it interacts with gut microbes.

When l-carnitine supplements reach the colon, gut microbes absorb the nutrient and convert it into trimethylamine (TMA), which is then further metabolized into trimethylamine N-oxide (TMAO) in the liver. High levels of TMAO in the blood have been linked to cardiovascular disease. However, when l-carnitine is naturally produced by the body, it bypasses the gut microbiota and does not lead to the production of TMAO.

To mitigate the harmful effects of l-carnitine supplements, the researchers conducted experiments using a pomegranate extract rich in polyphenols. Polyphenols are plant compounds with antioxidant properties that can interact with gut microbes. The results showed that the pomegranate extract significantly reduced the production of TMA by gut microbes, thus eliminating the potential risks associated with l-carnitine supplementation.

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The study’s findings suggest that incorporating ellagitannin-rich foods, such as pomegranates, raspberries, and walnuts, into your diet may help reduce the negative effects of l-carnitine supplements. By including these foods in your daily meals, you can not only improve your overall health but also potentially counteract the risks associated with l-carnitine supplementation.

Further research is being conducted to test the effectiveness of pomegranate extract in reducing TMAO production in human participants. This study aims to determine whether combining l-carnitine supplements with a pomegranate extract is more beneficial than taking the supplement alone.

In conclusion, while l-carnitine supplements have both benefits and risks, incorporating ellagitannin-rich foods into your diet may help mitigate the harmful effects of these supplements. By making informed choices about your dietary intake, you can optimize your exercise performance and overall health.

TAGGED:controversiallimitPomegranatesRisksScienceAlertsportssupplement
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