Friday, 31 Oct 2025
  • Contact
  • Privacy Policy
  • Terms & Conditions
  • DMCA
logo logo
  • World
  • Politics
  • Crime
  • Economy
  • Tech & Science
  • Sports
  • Entertainment
  • More
    • Education
    • Celebrities
    • Culture and Arts
    • Environment
    • Health and Wellness
    • Lifestyle
  • 🔥
  • Trump
  • VIDEO
  • House
  • White
  • ScienceAlert
  • Trumps
  • Watch
  • man
  • Health
  • Season
Font ResizerAa
American FocusAmerican Focus
Search
  • World
  • Politics
  • Crime
  • Economy
  • Tech & Science
  • Sports
  • Entertainment
  • More
    • Education
    • Celebrities
    • Culture and Arts
    • Environment
    • Health and Wellness
    • Lifestyle
Follow US
© 2024 americanfocus.online – All Rights Reserved.
American Focus > Blog > Tech and Science > Prescription Drug Combinations May Slow Alzheimer’s, Study Suggests : ScienceAlert
Tech and Science

Prescription Drug Combinations May Slow Alzheimer’s, Study Suggests : ScienceAlert

Last updated: May 7, 2025 12:05 am
Share
Prescription Drug Combinations May Slow Alzheimer’s, Study Suggests : ScienceAlert
SHARE

Millions of older adults rely on multiple prescription drugs to manage chronic illnesses on a daily basis. While polypharmacy is often necessary, it has been associated with various negative health outcomes in older adults, including memory problems, increased risk of falls, and greater frailty. The most common prescription drugs involved in polypharmacy are those used to treat conditions such as high blood pressure, high cholesterol, and depression – all of which are known risk factors for Alzheimer’s disease.

Recent research in mice suggests that certain combinations of prescription drugs may have a positive impact on memory and signs of Alzheimer’s disease. However, the effects seem to vary based on the sex of the mice. To further explore the relationship between polypharmacy and Alzheimer’s disease, an experiment was conducted using mice genetically altered to develop Alzheimer’s-like brain changes, including amyloid plaques – a key feature of the disease associated with memory loss.

Two different combinations of commonly prescribed drugs were tested on male and female mice. The results showed that polypharmacy had both positive and negative effects on Alzheimer’s disease progression, with outcomes differing based on the specific drug combinations used and the sex of the mice. For example, one drug combination had beneficial effects in male mice, while the same combination had little to no effect in females. Another combination showed different results, with benefits disappearing in males and memory worsening in females.

The study highlighted the complexity of polypharmacy’s effects on Alzheimer’s disease and the importance of considering sex differences in drug responses. Understanding these mechanisms is crucial for developing personalized and effective treatments for the disease. The findings also emphasized the need for tailored prescribing approaches for older adults, especially considering that older women are more likely to be polypharmacy users.

See also  Hints of exotic dark matter particles could be hiding in LHC data

As the global population ages, the risk of developing Alzheimer’s disease continues to rise. It is essential to explore all potential causes of the disease and ways to prevent it. Future translational studies from mice to humans are warranted to improve healthcare for the aging population and reduce risks associated with polypharmacy.

This article was written by Silvia Maioli, Associate Professor and Principal Researcher in Neurobiology at Karolinska Institutet, and Francesca Eroli, PhD Researcher in Neurobiology at Karolinska Institutet. It was originally published on The Conversation under a Creative Commons license.

TAGGED:AlzheimersCombinationsDrugprescriptionScienceAlertSlowStudysuggests
Share This Article
Twitter Email Copy Link Print
Previous Article Myha’la Lived Out Her Childhood Dream at the 2025 Met Gala Myha’la Lived Out Her Childhood Dream at the 2025 Met Gala
Next Article What Causes Climate Change? – Earth911 What Causes Climate Change? – Earth911
Leave a comment

Leave a Reply Cancel reply

Your email address will not be published. Required fields are marked *

Popular Posts

Ode to the Federal Scientist

Federal scientists play a crucial role in saving lives and advancing public health. In a…

April 5, 2025

Are Trump’s cuts to science the end of the endless frontier?

US President Donald Trump’s Executive Orders Impact Science Funding US President Donald Trump’s executive orders…

March 28, 2025

Astronomers Found the Most Self-Destructive Planet in the Sky

Astronomers have made a groundbreaking discovery by identifying the most self-destructive planet in the sky.…

July 2, 2025

Anthropic’s Claude AI became a terrible business owner in experiment that got ‘weird’

Claudius: The AI Middle-Manager Can AI agents truly replace human workers? This question was put…

June 29, 2025

Harvard Sues Trump Administration Over $2.2 Billion Federal Funding Freeze Amid Crackdown on Woke Campuses |

Harvard University Free Palestine Camp, organized in April-May 2024 in support of Palestine. (Credit: Dariusz…

April 22, 2025

You Might Also Like

Why identity-first security is the first defense against sophisticated AI-powered social engineering
Tech and Science

Why identity-first security is the first defense against sophisticated AI-powered social engineering

October 31, 2025
Your flight emissions are way higher than carbon calculators suggest
Tech and Science

Your flight emissions are way higher than carbon calculators suggest

October 31, 2025
USB-C Chargers: How to Choose the Best One
Tech and Science

USB-C Chargers: How to Choose the Best One

October 31, 2025
Teen victim tied to Washington Square Park drug bust ID’d as recent grad who moved to NYC to start new life, internship
Crime

Teen victim tied to Washington Square Park drug bust ID’d as recent grad who moved to NYC to start new life, internship

October 31, 2025
logo logo
Facebook Twitter Youtube

About US


Explore global affairs, political insights, and linguistic origins. Stay informed with our comprehensive coverage of world news, politics, and Lifestyle.

Top Categories
  • Crime
  • Environment
  • Sports
  • Tech and Science
Usefull Links
  • Contact
  • Privacy Policy
  • Terms & Conditions
  • DMCA

© 2024 americanfocus.online –  All Rights Reserved.

Welcome Back!

Sign in to your account

Lost your password?