The Trump administration’s decision to terminate or freeze over 3,800 research grants from the National Institutes of Health and the National Science Foundation in 2025 has sent shockwaves through the scientific community. These cuts, amounting to approximately $3 billion in remaining funds, have had a significant impact on a wide range of initiatives that are crucial for advancing knowledge and improving public health.
One of the most devastating cuts was the freezing of support for Northwestern University’s Lurie Cancer Center, a national hub for cancer research, care, and community outreach. With $77 million in remaining funds, this grant was the largest hit to any NIH grant. The loss of funding for such a vital cancer research institution is a major setback in the fight against this deadly disease.
Another important initiative that was affected by the cuts is the coordination hub of the National Science Foundation’s INCLUDES initiative. This $9 million grant aimed to make the STEM workforce more diverse by addressing systemic barriers to inclusion. The termination of this grant is a blow to efforts to increase diversity in the fields of science, technology, engineering, and mathematics.
Additionally, a grant aimed at understanding and reducing COVID-19 vaccine hesitancy among young Black adults in three Southern states was terminated, despite having $200,000 in unspent funds. This research is crucial for addressing disparities in vaccine uptake and improving public health outcomes.
The termination of a grant to investigate how neurons regulate specialized immune cells in the retina, which had $490,000 in remaining funding, is also concerning. The administration’s decision to cut funding for research on diverse immune cells raises questions about its commitment to understanding the complexities of the immune system and developing new treatments for diseases.
Furthermore, the University System of Maryland Louis Stokes Alliances for Minority Participation program, which aims to increase the number of underrepresented college students in Maryland, had a grant terminated with $1.7 million still to be spent. This loss of funding will hinder efforts to address education disparities and support underrepresented students in pursuing careers in STEM fields.
It is important to note that the data used for this analysis comes from Grant Witness, a project that tracks NIH and NSF grant terminations. While efforts were made to categorize grants by agency research areas based on grant abstracts, there may be inaccuracies due to delays in financial reporting. Additionally, the rapidly shifting landscape of funding priorities means that some funding may have been restored by the time this information is read.
Overall, the termination and freezing of these research grants have had a significant impact on critical scientific initiatives. It is crucial for policymakers to prioritize funding for research that addresses pressing public health issues and promotes diversity, equity, and inclusion in the scientific community.

