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American Focus > Blog > Health and Wellness > Study finds GLP-1 drug cut migraine frequency by nearly half
Health and Wellness

Study finds GLP-1 drug cut migraine frequency by nearly half

Last updated: June 20, 2025 3:27 pm
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Study finds GLP-1 drug cut migraine frequency by nearly half
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GLP-1 drugs have long been known for their effectiveness in treating diabetes and obesity. However, a recent study presented at the European Academy of Neurology congress suggests that these drugs may have another surprising benefit – reducing migraine frequency.

The pilot study, which can be found in the journal article published on PubMed, showed that GLP-1 agonists were able to decrease monthly migraine days by nearly half. The researchers behind the study speculated that the mechanism behind this reduction in migraine frequency could be linked to the drugs’ ability to lower intracranial pressure.

Dr. Alexandra Sinclair, a neurology expert from the University of Birmingham, praised the study for its significance and the questions it raises about the potential mechanisms of action of GLP-1 agonists. While she was not directly involved in the study, Dr. Sinclair has previously conducted research on the role of these drugs in reducing intracranial pressure.

This groundbreaking research opens up new possibilities for the use of GLP-1 drugs in treating migraines, a condition that affects millions of people worldwide. By targeting intracranial pressure, these drugs may offer a novel approach to managing migraine symptoms and improving the quality of life for migraine sufferers.

While the study’s findings are promising, further research is needed to fully understand the relationship between GLP-1 agonists and migraine frequency. Nevertheless, this study represents a significant step forward in our understanding of the potential therapeutic applications of these drugs beyond diabetes and obesity.

For more in-depth analysis and exclusive content, you can subscribe to STAT+ to access premium articles, newsletters, events, and news alerts. Subscribe now to stay updated on the latest developments in medical research and healthcare.

See also  Bariatric surgery rates plunge as patients turn to GLP-1 drugs
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