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American Focus > Blog > Tech and Science > Study on Mice Suggests Nose-Picking Has a Surprising Link With Alzheimer’s : ScienceAlert
Tech and Science

Study on Mice Suggests Nose-Picking Has a Surprising Link With Alzheimer’s : ScienceAlert

Last updated: August 10, 2025 3:40 pm
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Study on Mice Suggests Nose-Picking Has a Surprising Link With Alzheimer’s : ScienceAlert
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Study Suggests Link Between Nose Picking and Increased Risk of Dementia

A recent study published in 2022 has revealed a potential connection between the habit of picking your nose and a higher risk of developing dementia. While the link is not definitive and further research is needed, the findings shed light on a possible pathway that could contribute to the development of Alzheimer’s disease.

The study, conducted by researchers from Griffith University in Australia, focused on the impact of a bacterium called Chlamydia pneumoniae on the brain. This bacterium, known to cause pneumonia in humans, has been found in the brains of individuals with late-onset dementia.

Through experiments on mice, the researchers discovered that C. pneumoniae could travel from the nasal cavity to the brain via the olfactory nerve. When the nasal epithelium, the tissue lining the nasal cavity, was damaged, the bacteria were able to infect the nerves more severely.

As a result, the mouse brains exhibited an increase in the deposition of amyloid-beta protein, a response typically triggered by infections. Accumulation of this protein is a hallmark of Alzheimer’s disease and is often found in high concentrations in affected individuals.

Mouse Study Suggests Surprising Link Between Alzheimer's And Nose-Picking
Illustration of amyloid-beta protein plaques, in orange. (NIH/Flickr/PD)

Lead researcher James St John emphasized the significance of the findings, stating, “We’re the first to show that Chlamydia pneumoniae can travel directly from the nose to the brain and trigger processes resembling Alzheimer’s disease. While the study was conducted in mice, the implications for humans are concerning.”

Despite the promising results in mice, further research is required to confirm the same mechanisms in humans and determine the role of amyloid-beta plaques in Alzheimer’s disease. St John stressed the importance of investigating how these bacteria reach the brain in humans.

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While nose picking is a common habit among individuals, the potential risks highlighted by this study urge caution. St John and his team advise against nose picking and nose hair plucking due to the potential harm it can cause to the protective nasal tissue.

Future studies will delve into whether the increased deposition of amyloid-beta protein is a reversible immune response that can be mitigated with appropriate treatment. Understanding the complexities of Alzheimer’s disease is crucial in developing effective interventions to combat this prevalent neurodegenerative condition.

“Age is a significant risk factor for Alzheimer’s, but environmental factors such as bacterial and viral infections also play a role,” noted St John. “Continued research into these pathways is essential for advancing our understanding of the disease.”

The research findings were published in Scientific Reports, marking a significant step towards unraveling the mysteries of Alzheimer’s disease.

This article was originally published in November 2022 and has been adapted for WordPress.

TAGGED:AlzheimerslinkmiceNosePickingScienceAlertStudysuggestsSurprising
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