A recent clinical trial published in Nature Medicine has sparked controversy and skepticism among the scientific community. The study suggested that lung cancer patients treated with immunotherapy in the morning had a significant reduction in the risk of disease progression compared to those treated in the afternoon. However, concerns have been raised about the data and inconsistencies in the trial design.
The study is now under scrutiny as multiple scientists and investigators have pointed out discrepancies in the trial. Some of the main concerns include inconsistencies in the trial design listed on its clinicaltrials.gov registration page, errors in the submitted trial protocol, questionable progression-free survival data, and unusual findings related to side effects and adverse events.
Nature Medicine has acknowledged these concerns and has initiated an investigation into the study. Experts had previously expressed doubts about the biological plausibility of the study’s conclusions. The authors of the study have declined to comment for now, stating that they are working on a response to the issues raised.
The controversy surrounding this study highlights the importance of rigorous scientific research and scrutiny in the field of oncology. As more information emerges from the investigation, it will be crucial to ensure the integrity and reliability of the data and conclusions presented in the study. Stay tuned for further updates on this developing story.

