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American Focus > Blog > Health and Wellness > Subtle Differences Emerge Between FDA And CDC On COVID Vaccine Advice
Health and Wellness

Subtle Differences Emerge Between FDA And CDC On COVID Vaccine Advice

Last updated: June 1, 2025 7:00 am
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Subtle Differences Emerge Between FDA And CDC On COVID Vaccine Advice
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The Food and Drug Administration (FDA) recently announced a major policy shift regarding the approval of COVID-19 vaccines for healthy individuals under 65, including pregnant women. They proposed the need for new clinical trial research to determine the effectiveness of these vaccines before issuing updated approvals for a broader population. This update aligns with the Centers for Disease Control and Prevention (CDC), which included the option of COVID-19 vaccines for healthy children and pregnant women in their updated immunization schedule.

In a notable decision, the FDA limited the approval of Novavax’s nuvaxovid vaccine to adults 65 and older or individuals aged 12 to 64 with underlying health conditions that put them at increased risk for COVID-19. The FDA plans to require vaccine manufacturers to conduct booster trials to demonstrate the effectiveness of vaccines in individuals under 65 or without certain risks. These trials could take up to a year to complete, according to a report by STAT.

The concept of COVID-19 boosters is similar to annual flu shots, as they aim to update immunity to target evolving variants of the virus. Data from booster campaigns show lower hospitalization and death rates for boosted individuals, particularly among vulnerable populations categorized by age and underlying health conditions.

While COVID-19 vaccines are recommended for individuals over 65 and those with certain medical conditions, questions arise for healthy individuals under 65 without underlying health conditions who wish to receive the vaccine. The FDA and CDC seem to have subtly different advice for this demographic. It remains unclear whether these individuals can simply walk into a pharmacy and receive the vaccine or if they need permission from a doctor. Additionally, the cost of the vaccine may be a concern, as insurance companies may require medical documentation of an underlying condition before covering the cost, potentially leading to out-of-pocket expenses for patients.

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Top FDA officials advocate for an evidence-based approach to COVID-19 vaccination, aligning policies with those of European public health authorities. In Europe, outreach campaigns target specific subpopulations, such as the elderly and those with underlying health conditions, for vaccination. Unlike the FDA’s decision to narrow vaccine indications based on age, European agencies have not suggested similar changes for approved COVID-19 vaccines. Additionally, COVID-19 vaccines in Europe are typically available free of charge regardless of age or health status.

Overall, the evolving landscape of COVID-19 vaccine approvals and recommendations underscores the importance of evidence-based decision-making and targeted vaccination strategies to protect vulnerable populations and curb the spread of the virus.

TAGGED:AdviceCDCCOVIDDifferencesemergeFDAsubtlevaccine
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