Breakthrough in Brain Research: Simulation of Mouse Brain Offers Insight into Human Brain Functions
Understanding the complex workings of the brain has always been a challenge for scientists due to the limitations in studying living brains. However, a recent development in brain simulation technology has provided researchers with a groundbreaking tool for studying brain functions in unprecedented detail.
Led by a team from the Allen Institute in the US and the University of Electro-Communications in Japan, the simulation of a mouse’s brain is one of the most comprehensive models ever created. This simulation has the potential to revolutionize the study of neurological diseases such as Alzheimer’s by allowing researchers to model and analyze brain processes in ways never before possible.
The virtual brain model represents the entire cortex of a mouse, containing 9 million neurons and 26 billion synapses. While the mouse brain is not as complex as the human brain, there are similarities between the two that make this simulation a valuable tool for studying brain functions.
The simulation, created using the Fugaku supercomputer in Japan, consists of 86 interconnected regions and can perform quadrillions of calculations per second. This level of detail enables researchers to track the activity of individual neurons and observe how cognitive processes, consciousness, and diseases manifest in the brain.
Implications for Brain Research and Health
The development of this virtual brain simulation opens up new possibilities for studying various aspects of brain function without the need for invasive procedures. Researchers can use the model to investigate how seizures propagate in the brain, study brain wave patterns, and explore the interactions between different regions of the brain.
According to Anton Arkhipov, a computational neuroscientist at the Allen Institute, this milestone in brain simulation technology paves the way for building larger and more detailed models of the brain in the future. The ultimate goal is to create a full-scale model of the human brain to further our understanding of neurological disorders and brain health.
The researchers have already made significant discoveries using the mouse brain simulation, shedding light on brain wave synchronization and interhemispheric interactions. These findings could have far-reaching implications for the treatment of neurological conditions and the development of new therapies.
As we continue to unravel the mysteries of the brain, virtual brain models and advanced simulations will play a crucial role in advancing our knowledge of brain function and dysfunction. The possibilities are endless, and with ongoing research and technological advancements, we are on the brink of a new era in neuroscience.
For more information on this groundbreaking research, the study has been presented at the SC25 supercomputing conference and is available online for further exploration.

