Thursday, 30 Oct 2025
  • Contact
  • Privacy Policy
  • Terms & Conditions
  • DMCA
logo logo
  • World
  • Politics
  • Crime
  • Economy
  • Tech & Science
  • Sports
  • Entertainment
  • More
    • Education
    • Celebrities
    • Culture and Arts
    • Environment
    • Health and Wellness
    • Lifestyle
  • 🔥
  • Trump
  • VIDEO
  • House
  • White
  • ScienceAlert
  • Trumps
  • Watch
  • man
  • Health
  • Season
Font ResizerAa
American FocusAmerican Focus
Search
  • World
  • Politics
  • Crime
  • Economy
  • Tech & Science
  • Sports
  • Entertainment
  • More
    • Education
    • Celebrities
    • Culture and Arts
    • Environment
    • Health and Wellness
    • Lifestyle
Follow US
© 2024 americanfocus.online – All Rights Reserved.
American Focus > Blog > Tech and Science > Type 2 Diabetes Linked to Accelerated Brain Shrinkage, Study Reveals : ScienceAlert
Tech and Science

Type 2 Diabetes Linked to Accelerated Brain Shrinkage, Study Reveals : ScienceAlert

Last updated: November 21, 2024 6:48 pm
Share
Type 2 Diabetes Linked to Accelerated Brain Shrinkage, Study Reveals : ScienceAlert
SHARE

Aging and Brain Health: Understanding the Impact of White Matter Loss

As we age, a gradual loss of brain tissue is a natural process. However, a recent long-term brain scan study has shed light on how some individuals experience faster deterioration of neural connections once they reach middle age.

The study, which commenced in 1995, revealed that individuals showing higher losses in white matter – the tissue that houses nerve fibers – have an 86 percent higher risk of developing mild cognitive impairment (MCI).

Participants with type 2 diabetes exhibited significant white matter loss over time, leading to a 41 percent increased risk of MCI compared to those without metabolic disorders. Additionally, individuals with biomarkers of dementia in their cerebrospinal fluid (CSF) faced a nearly 50 percent higher risk of cognitive impairment.

Interestingly, individuals with both diabetes and biomarkers of amyloid plaques, associated with Alzheimer’s disease, had a 55 percent increased risk of cognitive impairment.

Long tubes with pink insides
Colored scanning electron micrograph of myelinated nerve fibers (axons). Axons are the main component of white matter in the brain. (Science Photo Library/Canva)

The study, led by neuroscientists at Johns Hopkins University, emphasizes the close association between white matter volume changes and cognitive function in aging. It suggests that white matter degeneration plays a crucial role in cognitive decline.

Insulin resistance, a key factor in amyloid plaque formation, may promote Alzheimer’s disease pathology, accelerating the progression from normal cognition to MCI in individuals with diabetes.

Conducted over 27 years with 185 mostly well-educated and White participants with a family history of dementia, the study underscores the importance of monitoring white matter changes in cognitive health.

While the findings may need further validation in diverse populations, the study’s extensive duration sets it apart from shorter MRI studies, providing valuable insights into brain changes over time.

See also  Being Bored Could Actually Be Good For Your Brain, Scientists Reveal : ScienceAlert

With 60 participants progressing to MCI and 8 developing dementia, the study highlights the normal age-related loss of gray matter and the accelerated deterioration of white matter, particularly in middle age.

Controlling diabetes is suggested as a modifiable risk factor to reduce the risk of Alzheimer’s dementia, with recent research indicating a 35 percent lower dementia risk in patients treated for type 2 diabetes.

Physician-scientist Shohei Fujita, in an invited commentary for JAMA’s Neurology, commends the study’s extended timeline and hopes it will lead to targeted interventions for individuals prone to progressive brain changes.

Considering gender and race as crucial variables in future research, the study underscores the variability in cognitive decline and dementia progression among individuals.

The study, published in JAMA Network, opens new avenues for understanding the impact of white matter loss on cognitive health and potential interventions to mitigate cognitive decline.

TAGGED:AcceleratedbrainDiabetesLinkedRevealsScienceAlertshrinkageStudyType
Share This Article
Twitter Email Copy Link Print
Previous Article The Banana That Made Me Sick to My Stomach The Banana That Made Me Sick to My Stomach
Next Article The Zephaniah forest The Zephaniah forest
Leave a comment

Leave a Reply Cancel reply

Your email address will not be published. Required fields are marked *

Popular Posts

Your gaming PC is overdue for an upgrade—Windows 11 Pro can fix that

Are you still using Windows 10 on your gaming PC? If so, it's time to…

May 15, 2025

Anti-Trump former Republican David Jolly considers run for Florida governor

David Jolly Eyes Florida Governor's Race as a Democratic Contender David Jolly, the former congressman…

March 25, 2025

Inside Miniature Dioramas, Flying Saucers Drift Across Extraterrestrial Landscapes — Colossal

Caroline Dewison, the talented artist behind A House of Wonders, creates intricate miniature scenes within…

December 6, 2024

Charlie Kirk’s Widow Erika Says She Forgives His Killer

Erika Kirk, the widow of Charlie Kirk, made a powerful statement at his memorial service…

September 21, 2025

We Earthlings: Know AI’s Water Impact

Generative artificial intelligence, such as ChatGPT, has become increasingly popular for answering questions and providing…

March 18, 2025

You Might Also Like

Nanotyrannus: Dinosaur skeleton settles long debate over ‘tiny T. rex’ fossils
Tech and Science

Nanotyrannus: Dinosaur skeleton settles long debate over ‘tiny T. rex’ fossils

October 30, 2025
Scott Clifton Reveals Bold and the Beautiful Planned to Kill Liam
Entertainment

Scott Clifton Reveals Bold and the Beautiful Planned to Kill Liam

October 30, 2025
A Signal Hidden Deep in Your Brain Could Track Parkinson’s Symptoms : ScienceAlert
Tech and Science

A Signal Hidden Deep in Your Brain Could Track Parkinson’s Symptoms : ScienceAlert

October 30, 2025
Scenes from JS Disrupt | JS
Tech and Science

Scenes from JS Disrupt | JS

October 30, 2025
logo logo
Facebook Twitter Youtube

About US


Explore global affairs, political insights, and linguistic origins. Stay informed with our comprehensive coverage of world news, politics, and Lifestyle.

Top Categories
  • Crime
  • Environment
  • Sports
  • Tech and Science
Usefull Links
  • Contact
  • Privacy Policy
  • Terms & Conditions
  • DMCA

© 2024 americanfocus.online –  All Rights Reserved.

Welcome Back!

Sign in to your account

Lost your password?