Friday, 31 Oct 2025
  • Contact
  • Privacy Policy
  • Terms & Conditions
  • DMCA
logo logo
  • World
  • Politics
  • Crime
  • Economy
  • Tech & Science
  • Sports
  • Entertainment
  • More
    • Education
    • Celebrities
    • Culture and Arts
    • Environment
    • Health and Wellness
    • Lifestyle
  • 🔥
  • Trump
  • VIDEO
  • House
  • White
  • ScienceAlert
  • Trumps
  • Watch
  • man
  • Health
  • Season
Font ResizerAa
American FocusAmerican Focus
Search
  • World
  • Politics
  • Crime
  • Economy
  • Tech & Science
  • Sports
  • Entertainment
  • More
    • Education
    • Celebrities
    • Culture and Arts
    • Environment
    • Health and Wellness
    • Lifestyle
Follow US
© 2024 americanfocus.online – All Rights Reserved.
American Focus > Blog > Health and Wellness > Use of ‘doxy PEP’ to reduce STIs appears to fuel some antibiotic resistance
Health and Wellness

Use of ‘doxy PEP’ to reduce STIs appears to fuel some antibiotic resistance

Last updated: July 9, 2025 2:15 pm
Share
Use of ‘doxy PEP’ to reduce STIs appears to fuel some antibiotic resistance
SHARE

The rise in antibiotic resistance in gonorrhea isolates following the endorsement of using the antibiotic doxycycline for post-exposure prophylaxis (PEP) is a concerning development. A recent study published in the New England Journal of Medicine reported a significant increase in resistance to tetracycline, the antibiotic class to which doxycycline belongs, in gonorrhea isolates collected nationwide. This rise in resistance was also observed in other bacterial pathogens carried by individuals who took doxy PEP.

Yonatan Grad, the senior author of the study, emphasized the benefits of using doxy PEP for controlling STIs like chlamydia and syphilis, as well as reducing rates of congenital syphilis. However, the study highlighted the cost of this approach, which is the increasing resistance in other bacterial pathogens. This evidence indicates that the theoretical concern of antibiotic resistance driving by doxy PEP is now a reality.

Several studies have shown the effectiveness of using a single dose of doxycycline within 72 hours of unprotected sex in reducing STI rates. However, the rise in antibiotic resistance poses a significant challenge to this approach. While countries like the United States, Germany, and Australia have adopted the use of doxy PEP, others are cautious or discourage its use due to concerns about antibiotic stewardship.

Gonorrhea is known for its ability to develop resistance to antibiotics over time. Currently, ceftriaxone is the recommended first-line treatment for gonorrhea, and resistance to tetracycline does not impact its effectiveness. However, there are already strains of gonorrhea resistant to ceftriaxone, mainly circulating in Asia. The development of new antibiotics for gonorrhea treatment is underway, but the concern remains about the potential for future resistance.

See also  The Future Of Researchers In The U.S. Is In Jeopardy

Experts not involved in the study expressed their lack of surprise at the findings, highlighting the ongoing challenge of antibiotic resistance in the context of STI treatment. The study underscores the importance of balancing the benefits of PEP with the potential risks of driving antibiotic resistance in other bacterial infections. Efforts to address this issue through continued research and surveillance are crucial to safeguarding the effectiveness of antibiotics in combating STIs. The importance of monitoring the evolving resistance patterns in gonorrhea has been underscored by recent findings, according to Barbara Van Der Pol, a professor of medicine and public health at the University of Alabama at Birmingham. Van Der Pol emphasized the need for ongoing surveillance of Neisseria gonorrhoeae for public health purposes.

Jeanne Marrazzo, an expert in sexually transmitted infections (STIs), raised concerns about the temporary closure of the CDC laboratory responsible for surveillance and testing of gonorrhea resistance patterns. Marrazzo, who previously served as the director of the National Institute of Allergy and Infectious Diseases, warned that without adequate resources for analysis, crucial data may be compromised.

Despite the findings, Marrazzo does not believe it is time to reconsider the use of doxycycline post-exposure prophylaxis (PEP). However, she suggested that the benefits of doxy PEP may be temporary and that a more sustainable solution would be the development of an effective vaccine for gonorrhea.

Dr. Grad, another expert in the field, acknowledged the challenges of discontinuing the use of doxy PEP, as at-risk populations have already adopted this practice, even in the absence of formal endorsements from public health authorities. A recent study in the Netherlands revealed that a significant portion of individuals had used doxy PEP informally, indicating a strong intention to continue its use.

See also  How DNA shapes reproductive health, fertility and even life expectancy

Despite the difficulty in halting the use of doxy PEP, Grad emphasized the clinical benefits of this practice in reducing rates of syphilis and chlamydia. The ongoing discussion surrounding the use of doxy PEP highlights the complex nature of STI prevention and the importance of ongoing research and surveillance in combating antibiotic resistance in gonorrhea.

In conclusion, the need for continued monitoring of gonorrhea resistance patterns and the development of sustainable prevention strategies remains a top priority in the field of public health. The findings discussed by Van Der Pol, Marrazzo, and Grad underscore the importance of vigilance and collaboration in addressing the challenges posed by antibiotic resistance in STIs.

TAGGED:AntibioticAppearsdoxyFuelPepReduceresistanceSTIs
Share This Article
Twitter Email Copy Link Print
Previous Article Julian McMahon’s Grief-Torn Family Open Up About His Death From Cancer Julian McMahon’s Grief-Torn Family Open Up About His Death From Cancer
Next Article Don’t Take a Google Pixel Smartphone to This Holiday Destination Don’t Take a Google Pixel Smartphone to This Holiday Destination
Leave a comment

Leave a Reply Cancel reply

Your email address will not be published. Required fields are marked *

Popular Posts

WATCH: Natalie Winters Delivers An EPIC Response to CNN Hack After He Asks a Stupid Question About Her Journalistic Credentials |

Credit: CNN screenshot This Week's Lesson in Journalistic Credibility In an unexpected twist during a…

April 23, 2025

NFL Power Rankings Week 8: Are Packers, Steelers, Seahawks contenders?

The Week 8 Power Rankings are out, and it's time to dive deep into each…

October 22, 2024

Giant atoms ‘trapped’ for record time at room temperature

Controlling giant atoms could lead to more powerful quantum computerskoto_feja/iStockphoto/Getty Images Giant atoms have emerged…

June 14, 2025

U.S. adult obesity rate fell in 2023, as use of GLP-1 meds rose

The findings showed that the obesity rate in the United States decreased from 46.2% in…

December 13, 2024

Pratt Institute Fall 2025 Ready-to-Wear Collection

Pratt's Graduating Class Showcase: A Blend of Creativity and Innovation This year, Pratt Institute's graduating…

May 19, 2025

You Might Also Like

How Architect Michael Murphy Is Rethinking The Value Of Design
Health and Wellness

How Architect Michael Murphy Is Rethinking The Value Of Design

October 31, 2025
Judges order contingency funds for SNAP payments during shutdown
Health and Wellness

Judges order contingency funds for SNAP payments during shutdown

October 31, 2025
Research shows that improved home ventilation can ease asthma symptoms, advance public health
Health and Wellness

Research shows that improved home ventilation can ease asthma symptoms, advance public health

October 31, 2025
Public Health Is Much More Than Vaccines
Health and Wellness

Public Health Is Much More Than Vaccines

October 31, 2025
logo logo
Facebook Twitter Youtube

About US


Explore global affairs, political insights, and linguistic origins. Stay informed with our comprehensive coverage of world news, politics, and Lifestyle.

Top Categories
  • Crime
  • Environment
  • Sports
  • Tech and Science
Usefull Links
  • Contact
  • Privacy Policy
  • Terms & Conditions
  • DMCA

© 2024 americanfocus.online –  All Rights Reserved.

Welcome Back!

Sign in to your account

Lost your password?