Here are the 49 US AI startups that have raised $100M or more in 2025

The year 2024 was a groundbreaking year for the AI industry in the United States and globally. With 49 startups raising funding rounds of $100 million or more, the sector saw significant growth and investment. Three companies even raised more than one "mega-round," while seven companies secured funding rounds of $1 billion or larger.

Looking ahead to 2025, the year has already proven to be on par with 2024 in terms of companies raising rounds of $100 million and above. Furthermore, there has been a notable increase in the number of companies securing multiple funding rounds exceeding $100 million compared to the previous year.

Here is a comprehensive list of U.S. AI companies that have raised $100 million or more this year:

November:

• Anysphere: Raised $2.3 billion in a funding round valuing the company at $29.3 billion.
• Parallel: Secured a $100 million Series A round co-led by Index Ventures and Kleiner Perkins.
• Hippocratic AI: Raised $126 million in a Series C round valuing the company at $3.5 billion.

  October:

• Fireworks AI: Raised $250 million in a Series C round valuing the company at $4 billion.
• Uniphore: Valued at $2.5 billion after a $260 million Series F round.
• Sesame: Raised a $250 million Series B round co-led by Sequoia and Spark Capital.
• OpenEvidence: Secured a $200 million Series C round valuing the company at $6 billion.
• Lila Sciences: Announced a $350 million Series A round led by Braidwell and Collective Global.
• Reflection AI: Raised a $2 billion Series B round led by Nvidia.
• EvenUp: Secured a $150 million Series E round valuing the company at over $2 billion.

  September:

• Periodic Labs: Raised $300 million in a seed round.
• Cerebras Systems: Secured a $1.1 billion Series G round valuing the company at $8.1 billion.
• Modular: Announced a $250 million funding round.
• Distyl AI: Raised $175 million in a Series B round valuing the startup at $1.8 billion.
• Upscale AI: Raised $100 million in a seed round.
• Groq: Secured a $750 million Series E round valuing the company at nearly $6.9 billion.
• Invisible Technologies: Valued at $2 billion after a $100 million fundraise.
• Cognition AI: Raised $400 million in a Series C round valuing the company at $10.2 billion.
• Baseten: Raised $150 million in a Series D round valuing the company at $2.1 billion.
• Sierra: Raised $350 million in a round led by Greenoaks Capital.
• You.com: Raised $100 million in a Series C round led by Cox Enterprises.
• Anthropic: Announced a $13 billion Series F round valuing the company at $183 billion.

  August:

• EliseAI: Raised $250 million in a Series E round valuing the startup at $2.2 billion.
• Decart: Raised $100 million at a $3.1 billion valuation.

  July:

• Fal: Raised $125 million in a Series C round valuing the company at $1.5 billion.
• Ambience Healthcare: Secured a $243 million Series C round led by Oak HC/FT and Andreessen Horowitz.
• Reka AI: Raised $110 million in a funding round that included Snowflake and Nvidia.
• Thinking Machines Lab: Raised $2 billion led by Andreessen Horowitz.
• OpenEvidence: Raised $210 million at a $3.5 billion valuation.
• Harmonic: Raised $100 million in a Series B round led by Kleiner Perkins.

  June:

• Abridge: Raised $300 million in a Series E round valuing the company at $5.3 billion.
• Harvey: Raised $300 million in a Series E round valuing the company at $5 billion.
• Tennr: Raised $101 million in a Series C round valuing the company at $605 million.
• Glean: Announced a $150 million Series F round valuing the company at $7.25 billion.
• Anysphere: Raised $900 million in a Series C round valuing the company at nearly $10 billion.

  May:

• Snorkel AI: Raised $100 million in a Series D round valuing the company at $1.3 billion.
• LMArena: Secured $100 million in a seed round valuing the company at $600 million.
• TensorWave: Raised $100 million in a Series A round.

  April:

• SandboxAQ: Closed a $450 million Series E round valuing the company at $5.7 billion.
• Runway: Raised $308 million in a Series D round valuing the company at $3 billion.

  March:

• OpenAI: Raised $40 billion in a funding round valuing the startup at $300 billion.
• Nexthop AI: Raised $110 million in a Series A round.
• Insilico Medicine: Raised $110 million in a Series E round valuing the company at $1 billion.
• Celestial AI: Raised $250 million in a Series C round valuing the company at $2.5 billion.
• Lila Sciences: Raised $200 million in a seed round.
• Reflection.AI: Raised $130 million in a Series A round.
• Turing: Closed a $111 million Series E round valuing the startup at $2.2 billion.
• Shield AI: Raised $240 million in a Series F round valuing the company at $5.3 billion.
• Anthropic: Raised $3.5 billion in a Series E round valuing the startup at $61.5 billion.

  February:

• Together AI: Raised $305 million in a Series B round valuing the company at $3.3 billion.
• Lambda: Raised $480 million in a Series D round valuing the startup at nearly $2.5 billion.
• Abridge: Valued at $2.75 billion in a Series D round.
• Eudia: Raised $105 million in a Series A round.
• EnCharge AI: Raised $100 million in a Series B round.
• Harvey: Raised $300 million in a Series D round valuing the company at $3 billion.

  January:

• ElevenLabs: Raised $180 million in a Series C round valuing the company at over $3 billion.
• Hippocratic AI: Raised $141 million in a Series B round valuing the company at over $1.6 billion.

  The AI industry continues to see robust growth and investment in 2025, with numerous companies securing substantial funding rounds to fuel their innovation and expansion. It will be interesting to see how the sector evolves and develops in the coming months and years.