Space Mice: A Giant Leap for Mammalian Reproduction
Four brave mice embarked on a groundbreaking journey to space as astronauts. Only one returned, but she came back not just as a survivor, but as a mother. This seemingly simple event could hold the key to humanity’s future beyond Earth.
On 31 October, China launched four mice – numbered 6, 98, 154, and 186 – aboard the Shenzhou-21 spacecraft to the country’s space station, orbiting roughly 400 kilometers above Earth. For two weeks, these rodents experienced microgravity, space radiation, and the unique conditions of life in orbit before safely returning on 14 November. Surprisingly, on 10 December, one of the female mice gave birth to nine healthy pups.
In a previous study, researchers used sperm from space-exposed mice to fertilize female mice on Earth. This new experiment resulted in six surviving offspring, indicating that short-term spaceflight did not impair the mice’s reproductive capabilities.
Wang Hongmei, a researcher at the Chinese Academy of Sciences’ Institute of Zoology, highlighted the importance of this discovery, as mice share genetic similarities with humans and respond to physiological stresses in ways that reflect human biology. If spaceflight had a detrimental effect on mammalian reproduction, mice would exhibit signs of it first.
Despite facing challenges during the mission, such as an unexpected extension due to a change in the return schedule, the ground team managed to ensure the mice’s well-being by providing emergency rations from the astronauts’ supplies. Soy milk emerged as the safest food option, and an AI monitoring system tracked the mice’s activities to predict supply needs accurately.
Living in carefully controlled conditions, the mice followed a structured routine with balanced nutrition, dental care, and hygiene maintenance. Researchers will closely monitor the “space pups” for any physiological changes resulting from their mother’s space exposure and assess their reproductive capabilities in the future.
The long-term goal of such experiments extends beyond mice, aiming to understand the effects of reduced gravity and space radiation on mammalian reproduction before embarking on long-duration space missions or establishing settlements on other celestial bodies.
While one mouse giving birth is just the beginning, it signifies a promising step towards unraveling the mysteries of reproduction in space. The implications of this study could pave the way for humanity’s expansion into the cosmos.
This article was originally published by Universe Today. Read the original article.

