When Anthony Letai assumed leadership of the National Cancer Institute in September, he inherited a tumultuous landscape in the world of cancer research. The federal government had recently terminated billions of dollars in research grants, only for those grants to be reinstated by the courts. Additionally, there were reports of mass firings within federal agencies, including the NCI’s communications department. To add to the chaos, the government faced the longest shutdown in history due to disagreements over healthcare policies.
Despite the challenging circumstances, Letai’s appointment as NCI director brought a sense of hope and stability to the cancer research community. As a renowned physician-scientist with significant contributions to the development of Venclexta, a crucial drug for treating certain blood cancers, Letai was seen as a beacon of expertise and leadership. Many believed that his background and accomplishments would help steer the NCI towards a more stable and productive future.
In a conversation with STAT, Letai expressed his commitment to reassuring the public that the NCI remains steadfast in its mission to combat cancer and alleviate the suffering caused by the disease. He emphasized the importance of communication and transparency in conveying the institute’s ongoing efforts and progress in cancer research.
As Letai embarks on his tenure as NCI director, his primary focus is to instill confidence and a sense of purpose within the organization. Despite the challenges and uncertainties that lie ahead, Letai’s leadership and dedication to advancing cancer research offer a glimmer of hope for the future of cancer treatment and prevention.

