New Technique Allows Light to Penetrate Entire Human Head for Non-Invasive Brain Imaging
Scientists have recently unveiled a groundbreaking method for non-invasive brain imaging that involves shining light through the entire head, from one side to the other. This innovative approach expands the capabilities of functional near-infrared spectroscopy (fNIRS), the current best portable and low-cost method for monitoring brain activity.
Traditionally, fNIRS can only penetrate a few centimeters into the brain, requiring larger and more expensive MRI machines for deeper exploration. However, a team of researchers from the University of Glasgow in Scotland has successfully enhanced the sensitivity of fNIRS to allow light to travel through the complex layers of bone, neurons, and tissue that make up the human head.
To achieve this feat, the researchers boosted the strength of the near-infrared laser within safe limits and implemented a more advanced collection setup. Despite only a small number of photons passing through the head during experiments, the results show promise for future portable imaging technologies that can provide deeper insights into brain function without invasive procedures.
The study, published in Neurophotonics, emphasizes the potential of extending non-invasive light-based brain imaging technologies to capture critical biomarkers deep within the adult human head.

While the new technique demonstrated success in one out of eight study participants, further refinements are needed to optimize the process for a wider range of individuals. The researchers acknowledge the specific requirements and extended scanning time necessary for this method but highlight the significant breakthrough in achieving light penetration through the human head.
Computer models based on detailed 3D head scans were instrumental in predicting photon movement through the skull, validating the accuracy of the collected light data. The study also revealed that light follows specific paths through the head, including regions with higher transparency such as cerebrospinal fluid, offering insights for more targeted brain scans in the future.
The potential applications of this technology are vast, ranging from improved stroke detection to enhanced tumor imaging, making brain scans more accessible and efficient for a broader population. While further advancements are needed to streamline the process, the research lays a solid foundation for future imaging devices that delve deeper into brain function.
As the field of non-invasive brain imaging continues to evolve, this study paves the way for bridging the gap between portable devices like EEG and high-resolution instruments such as fMRI. The implications of this research are profound, promising a new era of affordable and advanced brain imaging technologies.
The findings of this study offer a glimpse into the immense potential of optical modalities in understanding brain function across various stages of life, from childhood development to disease management in adulthood. With further advancements and refinements, non-invasive brain imaging could revolutionize the way we diagnose and treat neurological conditions.