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American Focus > Blog > Tech and Science > Did Disease Defeat Napoleon? | Scientific American
Tech and Science

Did Disease Defeat Napoleon? | Scientific American

Last updated: August 10, 2025 8:30 am
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Did Disease Defeat Napoleon? | Scientific American
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Napoleon’s ill-fated campaign against the Russian Empire in 1812 has long been considered one of the most costly wars in history. While many soldiers perished in battle, succumbed to frostbite, or died of starvation, a new study suggests that diseases may have played a significant role in the high death toll.

According to a recent preprint study by microbiologist RĂ©mi Barbieri and his team at Paris City University, previously unidentified pathogens may have been responsible for a large number of deaths among Napoleon’s troops. While historical records indicate that doctors diagnosed typhus and trench fever among the soldiers, Barbieri’s team found traces of Salmonella enterica and Borrelia recurrentis in the preserved teeth of fallen soldiers.

Salmonella enterica is known to cause typhoid fever, while Borrelia recurrentis is responsible for relapsing fever, transmitted mainly by body lice. These diseases, in combination with the harsh conditions of the campaign, could have easily led to the demise of weakened soldiers living in unsanitary environments.

Although the sample size of 13 soldiers examined by Barbieri’s team is small, their findings shed new light on the potential role of these pathogens in the high mortality rate during Napoleon’s retreat from Russia. While further research is needed to confirm these findings, it is clear that diseases may have been a significant factor in the loss of life during this historic military campaign.

Napoleon himself managed to survive the retreat almost unscathed, but the heavy losses suffered by his army ultimately led to his defeat at the Battle of Waterloo in 1815. The study underscores the importance of understanding the role of diseases in shaping the outcomes of historical conflicts.

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This article, originally published in Spektrum der Wissenschaft, highlights the ongoing research into the impact of diseases on historical events. As we continue to uncover new insights into the past, it is crucial to support scientific journalism that brings these discoveries to light.

If you are interested in supporting science journalism and ensuring that impactful stories like these are shared, consider subscribing to Scientific American. By becoming a subscriber, you can help fund the coverage of groundbreaking research and support the work of scientists around the world. Click here to subscribe and join us in standing up for science.

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