Wednesday, 11 Jun 2025
  • Contact
  • Privacy Policy
  • Terms & Conditions
  • DMCA
logo logo
  • World
  • Politics
  • Crime
  • Economy
  • Tech & Science
  • Sports
  • Entertainment
  • More
    • Education
    • Celebrities
    • Culture and Arts
    • Environment
    • Health and Wellness
    • Lifestyle
  • 🔥
  • Trump
  • House
  • VIDEO
  • White
  • ScienceAlert
  • Trumps
  • Watch
  • man
  • Health
  • Colossal
Font ResizerAa
American FocusAmerican Focus
Search
  • World
  • Politics
  • Crime
  • Economy
  • Tech & Science
  • Sports
  • Entertainment
  • More
    • Education
    • Celebrities
    • Culture and Arts
    • Environment
    • Health and Wellness
    • Lifestyle
Follow US
© 2024 americanfocus.online – All Rights Reserved.
American Focus > Blog > Tech and Science > Anti-Aging Cocktail Extends Mouse Lifespan by About 30 Percent : ScienceAlert
Tech and Science

Anti-Aging Cocktail Extends Mouse Lifespan by About 30 Percent : ScienceAlert

Last updated: May 28, 2025 2:20 am
Share
Anti-Aging Cocktail Extends Mouse Lifespan by About 30 Percent : ScienceAlert
SHARE

Scientists in Europe have recently conducted a groundbreaking study on anti-aging drug cocktails in mice, revealing promising results that could potentially revolutionize the field of longevity research. The study, led by a team of researchers from the Max Planck Institute in Germany, tested the effects of two drugs – rapamycin and trametinib – on extending the lifespan of mice.

Rapamycin, a drug commonly used to prevent organ rejection, has shown potential in extending lifespans in animal tests. Trametinib, on the other hand, has been known to extend the lifespan of fruit flies. However, the efficacy of these drugs in larger animals like mice had not been thoroughly explored until now.

The results of the study were nothing short of remarkable. When administered individually, rapamycin extended the lifespan of mice by 17 to 18 percent, while trametinib boosted longevity by 7 to 16 percent. However, when the two drugs were combined, the treated mice experienced a significant lifespan extension of around 26 to 35 percent.

Not only did the drug combination add extra years to the animals’ lifespans, but it also improved their overall health. The mice showed reduced chronic inflammation, delayed cancer onset, and a slower decline in heart function. Additionally, the growth of liver and spleen tumors was delayed in the treated mice, indicating a potential reduction in age-related illnesses.

Despite these promising findings, researchers caution against expecting a direct translation to human lifespan extension. Instead, the focus is on improving the quality of life in older age and potentially delaying the onset of age-related diseases.

Lead researcher Linda Partridge emphasizes the importance of further research in humans to determine the potential benefits of these drugs for prolonging healthspan. The team fed hundreds of mice regular doses of rapamycin, trametinib, or both from six months of age and monitored their survival rates for the remainder of their lives. The results showed a significant increase in median and maximum lifespans, with the combined treatment yielding the best outcomes.

See also  Scientists Have a Radical Plan to Grab a Sample of Venus's Toxic Atmosphere : ScienceAlert

One of the key findings of the study was that the benefits of the drug combination were not simply due to a higher dose. Both rapamycin and trametinib target different points in the same signaling pathway, and specific changes in gene expression were observed only when both drugs were administered together.

Importantly, no additional side effects were observed from combining the drugs, indicating a safe and potentially effective treatment option for extending healthspan in humans. Human trials for the drug combination could commence in the near future, as both rapamycin and trametinib are already approved for use in the US and European Union.

The research, published in the journal Nature Aging, represents a significant step forward in the quest for prolonging healthy aging and improving quality of life in later years. While the road to human application may still be long, the potential benefits of these anti-aging drug cocktails offer hope for a healthier and more vibrant aging process.

TAGGED:AntiAgingCocktailExtendslifespanmousepercentScienceAlert
Share This Article
Twitter Email Copy Link Print
Previous Article Here’s What Brands Celebrities Wore to the 2025 Cannes Film Festival Here’s What Brands Celebrities Wore to the 2025 Cannes Film Festival
Next Article This Portland collective keeps the city clean — and helps unhoused people find stability This Portland collective keeps the city clean — and helps unhoused people find stability
Leave a comment

Leave a Reply Cancel reply

Your email address will not be published. Required fields are marked *

Popular Posts

Koyo Kouoh, Curator Tapped for 61st Venice Biennale, Dies at 57

Koyo Kouoh, a prominent Cameroonian curator who was set to lead the 2026 Venice Biennale,…

May 13, 2025

‘Equality’ and ‘Equity’ Are Different. But in Thriving Schools, They Coexist (Opinion)

This historical context has created deep-rooted disparities that persist today, affecting access to resources, opportunities,…

September 11, 2024

Let’s Talk Toasters – Econlib

In a recent statement, Vice President-elect J.D. Vance made a controversial remark about imported toasters,…

January 3, 2025

Philadelphia man made bomb, mass shooting threats in fantasy football feud

A 25-year-old Philadelphia man found himself in hot water after taking a fantasy football feud…

September 19, 2024

Take the Final Nail Out of the Coffin: Election Denial Isn’t Dead

Election Denialism: A Lingering Threat to Democracy Following the 2024 general election, many hailed the…

February 3, 2025

You Might Also Like

Why Some Animals Live for Days and Others Live for Decades
Tech and Science

Why Some Animals Live for Days and Others Live for Decades

June 11, 2025
I Ditched my Smartphone For a Basic Phone. Here’s What Happened
Tech and Science

I Ditched my Smartphone For a Basic Phone. Here’s What Happened

June 11, 2025
‘Impossible’ particle that hit Earth may have been dark matter
Tech and Science

‘Impossible’ particle that hit Earth may have been dark matter

June 11, 2025
Standard Nuclear emerges from the ashes of a failed startup
Tech and Science

Standard Nuclear emerges from the ashes of a failed startup

June 11, 2025
logo logo
Facebook Twitter Youtube

About US


Explore global affairs, political insights, and linguistic origins. Stay informed with our comprehensive coverage of world news, politics, and Lifestyle.

Top Categories
  • Crime
  • Environment
  • Sports
  • Tech and Science
Usefull Links
  • Contact
  • Privacy Policy
  • Terms & Conditions
  • DMCA

© 2024 americanfocus.online –  All Rights Reserved.

Welcome Back!

Sign in to your account

Lost your password?