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American Focus > Blog > Tech and Science > Antidepressants Are Seeping Into Fish Everywhere – And It’s Changing Them : ScienceAlert
Tech and Science

Antidepressants Are Seeping Into Fish Everywhere – And It’s Changing Them : ScienceAlert

Last updated: August 27, 2024 9:25 pm
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Antidepressants Are Seeping Into Fish Everywhere – And It’s Changing Them : ScienceAlert
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Antidepressants have been a crucial tool in treating mental health conditions for decades, with millions of people worldwide benefiting from their effects since the 1950s. However, the impact of these drugs on the environment, specifically on freshwater fish, has been a topic of growing concern.

A recent study conducted by researchers delved into the effects of pharmaceutical pollution on male guppies, focusing on the antidepressant fluoxetine, commonly known as Prozac. The research revealed that even low levels of fluoxetine, similar to what fish may encounter in the wild, had detrimental effects on male guppies over time. These effects ranged from changes in physical condition to reproductive health, highlighting the potential risks posed by pharmaceutical pollution in aquatic ecosystems.

The issue of pharmaceutical pollution stems from the fact that when humans consume medication, only a portion of it is absorbed by the body, while the rest is excreted in urine. Wastewater treatment plants are not equipped to effectively remove these drug residues, leading to the release of vast quantities of pharmaceuticals into natural waterways. This widespread contamination poses a threat to aquatic organisms, impacting their behavior, physiology, and reproduction.

Fluoxetine, in particular, has been identified as one of the most commonly found pharmaceuticals in rivers, lakes, and streams globally, including in Australia. The drug’s ability to alter serotonin levels in the brain, which affects mood and behavior in humans, can also impact fish and other species due to shared biological receptors.

In a groundbreaking study, researchers exposed successive generations of wild guppies to fluoxetine over five years in a laboratory setting. The results showed that male guppies exposed to low levels of the drug exhibited poor physical condition, larger reproductive organs, and decreased sperm motility. These effects could potentially reduce the reproductive success of exposed males and disrupt the natural balance of aquatic ecosystems.

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Moreover, the study highlighted how fluoxetine exposure influenced the activity and hiding behavior of male guppies, affecting their ability to adapt to environmental changes and increasing their vulnerability to predators. These behavioral disturbances could have far-reaching implications for the survival and reproductive success of fish in the wild.

The research findings underscore the need for further investigation into the long-term effects of pharmaceutical pollution on aquatic wildlife. Understanding the impact of these contaminants is crucial for developing effective strategies to protect sensitive ecosystems and improve wastewater treatment processes. By raising awareness of the risks posed by pharmaceutical pollution, we can work towards mitigating its effects and safeguarding the health of our environment.

This post was written by Upama Aich, Bob Wong, and Giovanni Polverino, researchers from Monash University, and originally published on The Conversation under a Creative Commons license.

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