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Tech and Science

Cycling Linked to Lower Risk of Dementia, Study of Half a Million Finds : ScienceAlert

Last updated: June 14, 2025 4:20 am
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Cycling Linked to Lower Risk of Dementia, Study of Half a Million Finds : ScienceAlert
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How Regular Bicycle Commuting Can Reduce the Risk of Dementia

Recent research has shown that incorporating more bicycle commuting into your daily routine could potentially lower the risk of developing dementia. This study, conducted by researchers from the Huazhong University of Science and Technology in China and the University of Sydney, highlights the benefits of moderate exercise and cognitive stimulation in protecting against neurodegeneration.

By analyzing public health records of nearly half a million individuals, with an average age of around 56, the researchers identified a correlation between different modes of transportation and the incidence of dementia. The study categorized transportation methods into non-active (cars and public transport), walking, a combination of walking and non-active modes, and cycling either as the primary mode of transport or in conjunction with other methods.

Compared to non-active travelers, individuals who primarily cycled had a 19% lower risk of all-cause dementia, a 22% lower risk of Alzheimer’s disease, a 40% lower risk of young-onset dementia (before age 65), and a 17% lower risk of late-onset dementia.

graph with travel mode on the x axis, listing nonactive, walking, mixed-walking and cycling and mixed walking. on the y axis is incident dementia Hazard ratio. nonactive has a HR of 1.0, walking has a HR of more than 1, mixed walking slightly less than 1, cycling and mixed walking is less than 0.9
All-cause dementia risk for various travel modes. (Hou et al., JAMA Network Open, 2025)

The researchers suggest that promoting active travel strategies, particularly cycling, could significantly reduce the risk of dementia among middle-aged and older adults. This not only benefits individual cognitive health but also has broader public health implications.

Dementia is a multifaceted condition, influenced by various factors. Previous studies have linked spatial navigational abilities and brain volume to dementia risk, aligning with the findings that cyclists exhibited higher hippocampal volumes.

6 different angles of the brain showing color-coded structures.
The neuroimaging analyses provided evidence for positive associations between cycling and mixed-cycling mode and 10 regional gray matter volumes. (Hou et al., JAMA Network Open, 2025)

The physical activity demands of cycling, along with the cognitive challenges of route navigation and staying alert, contribute to its protective effects against dementia. However, individuals with the APOE4 gene variant associated with Alzheimer’s may not experience the same benefits from cycling.

While the study considered factors like age and education, it does not establish direct causation. Nonetheless, the strong association between cycling and reduced dementia risk aligns with existing research on the benefits of exercise for cognitive health.

As the global population ages, dementia is becoming a pressing issue. Encouraging methods to lower dementia risk, such as promoting cycling as a mode of transportation, could have significant public health implications.

The findings of this research have been published in JAMA Network Open.

TAGGED:cyclingdementiafindsLinkedMillionRiskScienceAlertStudy
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