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American Focus > Blog > Health and Wellness >  Early-onset cancer: the types that are on the rise
Health and Wellness

 Early-onset cancer: the types that are on the rise

Last updated: May 8, 2025 9:15 am
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 Early-onset cancer: the types that are on the rise
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Cancer before the age of 50 is a rare occurrence, but recent studies have shown a concerning increase in early-onset cancers in the United States. Researchers are eager to understand the reasons behind this trend and explore potential risk factors contributing to the rise in cancer cases among younger adults.

A comprehensive government study conducted by scientists from the National Cancer Institute analyzed data from over 2 million cancer diagnoses in individuals aged 15 to 49 between 2010 and 2019. The study revealed that breast, colorectal, kidney, and uterine cancers were among the most prevalent types of early-onset cancers showing significant increases in incidence rates. Notably, about 63% of the early-onset cancers were reported in women.

The findings of the study, published in the journal Cancer Discovery, highlighted a concerning pattern of rising cancer rates among younger age groups. Breast cancer accounted for the largest share of excess cancers, with approximately 4,800 additional cases recorded. Additionally, there were notable increases in colorectal, kidney, and uterine cancers compared to the rates observed in 2010.

While the study did not indicate a rise in death rates for most cancers in young adults, there were increasing mortality rates observed for colorectal, uterine, and testicular cancers. The reasons behind this alarming trend require further investigation, as the study lacked information on risk factors and access to healthcare. Experts believe that factors such as obesity, advances in cancer detection, and changes in screening guidelines could be contributing to the early diagnoses of certain cancer types.

For instance, the trend of women delaying childbirth to older ages could be a factor influencing the rise in breast cancer cases, as pregnancy and breastfeeding are known to reduce the risk of developing the disease. However, not all cancers showed a uniform trend of increase among younger adults. Some cancer types, such as lung and prostate cancers, exhibited a decline in incidence rates in individuals under 50.

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The decrease in lung cancer rates among younger adults is attributed to the long-standing decline in cigarette smoking, while the drop in prostate cancer cases is linked to updated guidelines discouraging routine PSA testing in younger men. The complex nature of cancer trends necessitates ongoing research and collaboration among experts to unravel the underlying causes and develop effective prevention and treatment strategies.

In conclusion, the rise in early-onset cancers in the United States underscores the importance of continued research and public health efforts to address the changing landscape of cancer incidence among younger adults. By understanding the factors driving this trend, healthcare professionals can work towards early detection, prevention, and improved outcomes for individuals affected by cancer at a young age.

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