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Tech and Science

Exercise may relieve depression as effectively as antidepressants

Last updated: January 7, 2026 8:35 pm
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Exercise has long been known to have a positive impact on mood, with many people reporting a mood-boost after physical activity. A recent updated review has shed light on just how powerful exercise can be in easing the symptoms of depression. Even light exercise, such as walking or gardening, has been found to be as effective as talking therapies or antidepressants in alleviating depressive symptoms.

Andrew Clegg, a researcher at the University of Lancashire in the UK, highlights the importance of exercise as a treatment option for those experiencing depressive symptoms. Previous studies, including a key review published by the Cochrane Library in 2013, have also shown that exercise can be as effective as standard therapies for managing depression, such as antidepressants and cognitive behavioural therapy (CBT).

Healthcare organizations, including the UK’s National Institute for Health and Care Excellence (NICE), recommend regular aerobic exercise for managing depression. The updated review, published by the Cochrane Library, analyzed results from 69 randomized controlled trials involving nearly 5000 adults with varying degrees of depression. The researchers found that exercise, whether low-intensity activities like gardening or brisk walking or more vigorous activities like sprinting, can moderately reduce the severity of depressive symptoms.

Furthermore, the review compared the effectiveness of exercise to other therapies such as CBT and antidepressants. Surprisingly, regular exercise was found to be equally as effective as these standard therapies in managing depression. Light to moderate exercise was found to be more effective than vigorous exercise, possibly due to the increased likelihood of adherence to less strenuous activities.

The mechanisms behind how exercise benefits mental health are not entirely clear, but researchers suggest that factors such as social interaction, learning new skills, and the release of myokines during exercise may play a role. Myokines are chemicals released from muscles that help reduce inflammation and promote the growth of new brain cells, potentially aiding in rewiring the brain and breaking negative thought patterns.

While the findings of the review support the recommendation of exercise for treating depression, researchers acknowledge the need for larger studies to better understand the specific types of exercise that are most beneficial for different individuals. Additionally, the possibility of the placebo effect influencing the results of the studies, as well as the relatively small sample sizes of the studies reviewed, suggest that more research is needed to solidify these conclusions.

In conclusion, exercise has been shown to be a valuable tool in managing depression, offering a natural and accessible treatment option for those experiencing depressive symptoms. Further research is needed to determine the most effective types of exercise for different individuals and to better understand the underlying mechanisms of how exercise impacts mental health. For individuals struggling with severe forms of depression, finding the motivation to exercise can be a difficult task. In such cases, cognitive behavioral therapy (CBT) or antidepressants may be recommended as effective treatment options, according to a recent review. The review also highlights that these alternative treatments are just as effective as exercise in managing depression.

Moreover, the type of exercise chosen may vary depending on the individual’s specific circumstances. Factors such as the underlying cause of depression can influence which type of exercise is most beneficial. For instance, someone dealing with stress-related depression may benefit more from activities like yoga or pilates, which focus on relaxation and mindfulness.

Despite these considerations, the overall consensus is that exercise offers both mental and physical health benefits. Dr. Stubbs emphasizes that various forms of exercise, whether it be running, going to the gym, or practicing yoga, can have positive effects on overall well-being. The key is to find an activity that is enjoyable and empowering for the individual.

In conclusion, while the choice of treatment for depression may vary from person to person, the importance of incorporating exercise into a wellness routine cannot be understated. Whether it’s through traditional forms of exercise or more holistic approaches like yoga, finding an activity that brings joy and fulfillment can make a significant difference in managing depression. Ultimately, the goal is to empower individuals to prioritize their mental and physical health through regular exercise.

TAGGED:AntidepressantsDepressionEffectivelyexerciseRelieve
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