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American Focus > Blog > Health and Wellness > Healthy lifestyle linked to lower diverticulitis risk, irrespective of genetic susceptibility
Health and Wellness

Healthy lifestyle linked to lower diverticulitis risk, irrespective of genetic susceptibility

Last updated: July 1, 2025 5:49 pm
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Healthy lifestyle linked to lower diverticulitis risk, irrespective of genetic susceptibility
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Maintaining a healthy lifestyle has long been associated with a lower risk of various health conditions, and a recent study published in the journal Gut highlights the connection between a healthy lifestyle and a reduced risk of diverticulitis. Diverticulitis is a condition characterized by inflamed or infected pouches that develop along the wall of the large intestine, leading to symptoms such as abdominal pain, bloating, and changes in bowel habits.

The study, which analyzed data from over 179,000 participants from three prospective studies, found that five key lifestyle factors were significantly associated with a lower risk of diverticulitis: smoking, weight (BMI), physical activity, fiber intake, and red/processed meat intake. Participants who adhered to a healthy lifestyle, characterized by a diet rich in fiber, regular exercise, not smoking, and maintaining a normal weight, were found to have a 12% lower risk of developing diverticulitis for every 1-point increase in their healthy lifestyle score.

Interestingly, the study also looked at the role of genetic factors in the development of diverticulitis. Participants with a higher genetic risk score were more likely to develop the condition, but the researchers found that a healthy lifestyle could offset this genetic susceptibility. Those with a healthy lifestyle score of 4-5 were significantly less likely to develop diverticulitis, even if they had a high genetic risk score.

The findings were consistent across different racial groups and were further validated in additional cohorts, highlighting the robustness of the results. The researchers concluded that adherence to a healthy lifestyle is key in reducing the risk of diverticulitis, regardless of one’s genetic predisposition.

It’s important to note that this study is observational and cannot establish causation. However, the results provide valuable insights into the role of lifestyle factors in the development of diverticulitis and underscore the importance of maintaining a healthy lifestyle for overall gut health.

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For more information on this study, you can access the full article in Gut titled “Lifestyle factors, genetic susceptibility and risk of incident diverticulitis: an integrated analysis of four prospective cohort studies and electronic health records-linked biobank.”

This research was provided by the British Medical Journal and emphasizes the impact of lifestyle choices on gut health and disease prevention.

TAGGED:diverticulitisgenetichealthyirrespectiveLifestyleLinkedRisksusceptibility
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