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American Focus > Blog > Health and Wellness > Long working hours may alter brain structure, preliminary findings suggest
Health and Wellness

Long working hours may alter brain structure, preliminary findings suggest

Last updated: May 13, 2025 3:54 pm
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Long working hours may alter brain structure, preliminary findings suggest
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Long working hours can have a significant impact on the structure of the brain, particularly in areas associated with emotional regulation and executive function. A recent study published in Occupational & Environmental Medicine suggests that overwork may induce neuroadaptive changes that could affect cognitive and emotional health.

The research, conducted on health care workers who regularly worked long hours (defined as 52 or more hours per week), utilized structural brain volume analysis to examine the effects of overwork on specific brain regions. Participants in the study underwent MRI scans to assess any potential changes in brain structure.

The findings revealed that individuals who worked long hours displayed significant alterations in brain regions linked to executive function and emotional regulation compared to those who worked standard hours. For example, the volume of the middle frontal gyrus, a key region involved in cognitive functions such as attention, working memory, and language processing, showed a 19% increase in individuals working long hours.

Other regions, such as the superior frontal gyrus and the insula, also exhibited peak increases in brain volume. These areas play crucial roles in attention, planning, decision-making, emotional processing, self-awareness, and understanding social context.

While the study provides valuable insights into the potential impact of overwork on brain health, the researchers caution that the findings are preliminary and more research is needed to establish a causal relationship. They emphasize the importance of addressing overwork as an occupational health concern and advocate for workplace policies that mitigate excessive working hours.

In conclusion, the study sheds light on the neurological consequences of long working hours and underscores the need for further research to better understand the mechanisms underlying these structural changes. By raising awareness of the potential risks associated with overwork, policymakers and employers can take steps to create healthier work environments that prioritize employee well-being.

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For more information on this study, you can refer to the article “Overwork and changes in brain structure: a pilot study” published in Occupational and Environmental Medicine.

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