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American Focus > Blog > Tech and Science > Many U.S. babies may lack gut bacteria that train their immune systems
Tech and Science

Many U.S. babies may lack gut bacteria that train their immune systems

Last updated: June 25, 2025 5:20 am
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Many U.S. babies may lack gut bacteria that train their immune systems
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The findings of a new study conducted by Persephone Biosciences suggest that about three quarters of babies born in the United States may lack the necessary levels of friendly gut microbes to protect against allergies, asthma, and eczema. The study, which involved over 400 babies, revealed that 24 percent of infants had no detectable levels of Bifidobacterium, a crucial gut microbe that aids in digesting sugars in breast milk.

Stephanie Culler, the cofounder and chief executive of Persephone Biosciences, expressed surprise at the lack of Bifidobacterium in such a significant number of infants. The absence of these fundamental bacteria was concerning, as they play a vital role in training the immune system and preventing allergic conditions. Babies with low levels of Bifidobacterium were found to be at least three times more likely to develop allergies, eczema, and asthma by the age of 2 compared to babies with expected levels of these bacteria.

The study also highlighted the impact of antibiotics on gut microbes, with babies who received antibiotics having a 3.3 times higher risk of developing allergic conditions. Changes in dietary habits, increased use of antibacterial products, and other environmental factors have contributed to the decline of Bifidobacterium in infants’ guts.

Interestingly, even vaginally born, breastfed babies were found to have low levels of Bifidobacterium, indicating that breastfeeding alone may not be sufficient to restore these important microbes. Additionally, babies born via C-section were more likely to have low or missing levels of Bifidobacterium.

Persephone Biosciences is currently investigating the use of a product containing Bifidobacterium, human milk sugars, and vitamin D to potentially increase the levels of these beneficial bacteria in infants. The long-term consequences of the absence of Bifidobacterium and the proliferation of potentially harmful bacteria in infants’ guts are still unknown, and the study aims to monitor the children’s health for seven years to assess the impact of these microbial imbalances. Results of the trial investigating the potential benefits of probiotics are expected to be released later this year. Probiotics have been studied extensively for their role in reducing the risk of developing inflammatory diseases such as asthma and eczema. Dr. Gilbert, a leading expert in the field, notes that while many trials have shown promising results, the use of probiotics in premature babies has raised concerns.

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In 2023, the U.S. Food and Drug Administration issued a warning against the use of probiotics in premature infants after a tragic incident in which a preterm baby died. While it is not definitively proven that the probiotic strain B. infantis was the cause of the baby’s death, the FDA erred on the side of caution. Despite this isolated incident, Dr. Gilbert emphasizes that hundreds of thousands of people use probiotics containing Bifidobacterium strains daily without any reported instances of infection.

For pregnant and lactating individuals, Dr. Gilbert suggests that there is likely no risk in taking Bifidobacterium probiotics. In fact, there may be significant benefits in transferring these beneficial organisms to their babies. By incorporating probiotics into their daily routine, pregnant and nursing individuals can potentially support their own health and that of their infants.

As the trial results are eagerly awaited, it is clear that probiotics continue to be a topic of interest and research in the medical community. Stay tuned for updates on the potential benefits of probiotics for inflammatory diseases and overall health. The Advantages of Using Renewable Energy Sources

In recent years, there has been a growing emphasis on the importance of utilizing renewable energy sources to combat the negative effects of climate change and to reduce our reliance on fossil fuels. Renewable energy sources, such as solar, wind, hydroelectric, and geothermal power, offer a number of advantages over traditional sources of energy. In this article, we will explore some of the key benefits of using renewable energy sources.

One of the primary advantages of using renewable energy sources is their ability to reduce greenhouse gas emissions. Unlike fossil fuels, which release large amounts of carbon dioxide and other pollutants into the atmosphere when burned, renewable energy sources produce little to no emissions. This helps to mitigate the effects of climate change and improve air quality, leading to a healthier environment for both people and wildlife.

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Another benefit of using renewable energy sources is their ability to create jobs and stimulate economic growth. The renewable energy industry is rapidly expanding, creating new opportunities for employment in sectors such as manufacturing, installation, and maintenance. In addition, investing in renewable energy projects can help to revitalize local economies and attract new businesses to a region.

Renewable energy sources also offer a more sustainable and reliable source of power compared to fossil fuels. Unlike coal, oil, and natural gas, which are finite resources that will eventually run out, renewable energy sources are inexhaustible and can be replenished naturally. This ensures a stable and consistent supply of energy for years to come, reducing the risk of energy shortages and price fluctuations.

In addition to their environmental and economic benefits, renewable energy sources can also help to diversify the energy grid and increase energy security. By harnessing a mix of renewable energy sources, such as solar, wind, and hydroelectric power, countries can reduce their dependence on imported fossil fuels and improve their energy independence. This can help to protect against geopolitical risks and ensure a more stable and resilient energy system.

Overall, the advantages of using renewable energy sources are clear. From reducing greenhouse gas emissions and creating jobs to promoting economic growth and increasing energy security, renewable energy offers a wide range of benefits for both the environment and society as a whole. As we continue to transition towards a more sustainable energy future, investing in renewable energy sources will be crucial in achieving a cleaner, greener, and more prosperous world. The sun was setting over the horizon, painting the sky in vibrant shades of orange and pink. As the last rays of sunlight disappeared behind the mountains, the world was bathed in a soft, golden glow. It was a picture-perfect moment, one that seemed to freeze time and hold the world in a moment of pure beauty.

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As the sky darkened and the stars began to twinkle overhead, the world came alive in a different way. The sounds of the night filled the air – the chirping of crickets, the rustle of leaves in the breeze, and the occasional hoot of an owl in the distance. The world seemed to hum with energy, as if it were alive and pulsing with its own heartbeat.

In the darkness, the world took on a different kind of beauty. The moon rose high in the sky, casting a silvery light over the landscape. Shadows danced across the ground, creating a sense of mystery and intrigue. The night was full of possibilities, full of magic and wonder.

As the night wore on, the world seemed to slow down. Time stretched out endlessly, each moment feeling like an eternity. The world was quiet and still, as if it were holding its breath in anticipation of what was to come.

And then, as the first light of dawn began to creep over the horizon, the world was bathed in a soft, pinkish glow. The birds began to chirp, the world began to stir, and life returned to the land once more. It was a new day, full of promise and potential.

As the sun rose higher in the sky, the world came alive with color and light. The flowers bloomed, the trees rustled in the breeze, and the world seemed to sing with joy. It was a new beginning, a fresh start, a chance to make the most of the day ahead.

And so, as the world woke up to a new day, it was filled with a sense of wonder and awe. The beauty of the world was on full display, and it was a reminder of the magic and mystery that surrounds us every day. It was a moment to pause, to appreciate, and to marvel at the beauty of the world around us.

TAGGED:BabiesbacteriagutImmuneLackSystemstrainU.S
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