Migraines and headaches are common conditions that affect over a third of the global population. According to a recent study published in Cell Reports Medicine, modern lifestyles and various triggers such as stress, sedentary activity, caffeine, alcohol, and poor-quality sleep contribute to the prevalence of these disorders.
The research, conducted by neurology experts from La Trobe University and Western Health, highlighted the impact of the COVID-19 pandemic on headache management. The study revealed that acute or chronic headaches following SARS-CoV-2 infection or vaccination have added to the global burden of migraines and headaches.
It is estimated that 2.8 billion people worldwide suffer from these debilitating conditions, with women aged 30–44 and individuals from higher-income countries being disproportionately affected. Migraines, although less common, are more disabling than general headaches.
The study emphasized the need for increased healthcare funding and recognition of migraines and headaches to support those affected. Despite advancements in diagnostic tools and treatment options, the prevalence of these disorders is expected to remain constant due to ongoing modern risk factors.
Tailored interventions and resources are recommended to reduce the burden of migraines and headaches in the future. The report stressed the urgency of prioritizing these conditions in global health agendas to improve recognition and management.
For further information, the study “Global, regional, and national burden of headache disorders, 1990–2021, with forecasts to 2050: A Global Burden of Disease study 2021” published in Cell Reports Medicine can be accessed with DOI: 10.1016/j.xcrm.2025.102348.
As the global community continues to address the challenges posed by migraines and headaches, awareness campaigns such as the Step4Migraine Walk aim to raise awareness and improve accessibility for individuals suffering from these conditions. It is essential to prioritize the recognition and management of migraines and headaches to alleviate the global burden and improve the quality of life for those affected.

