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American Focus > Blog > Tech and Science > Snakes Caught ‘Wiping’ Poison Off Frogs, Amidst Nature’s Toxic Arms Race : ScienceAlert
Tech and Science

Snakes Caught ‘Wiping’ Poison Off Frogs, Amidst Nature’s Toxic Arms Race : ScienceAlert

Last updated: October 29, 2025 11:50 am
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Predator-prey interactions are a constant battle of wits and survival in the natural world. Animals have evolved a variety of strategies to defend themselves against predators, including the use of toxins. The recent experiment conducted by biologist Valeria Ramírez Castañeda and her colleagues sheds light on how some animals, like the royal ground snakes, have developed unique ways to deal with toxic prey.

In the study, ten royal ground snakes collected from the Colombian Amazon were faced with a challenging predicament. After being deprived of food for several days in captivity, they were presented with three-striped poison dart frogs, known for their deadly toxins. Despite the unappetizing nature of the prey, four of the snakes boldly attacked and attempted to consume the frogs.

Before swallowing their meals, the snakes exhibited a fascinating behavior – dragging the frogs across the ground. This behavior is reminiscent of how some birds rub toxins off their prey before consuming them. The researchers noted that this behavior may be a defense mechanism to reduce exposure to the deadly toxins present in the frog’s skin.

The ability of animals to produce or acquire toxins as a defense mechanism has been a key evolutionary strategy for millions of years. From microbes to plants to animals, the use of toxins in biological warfare is a common phenomenon. In response, many species have evolved mechanisms to counteract these toxins and protect themselves from harm.

One of the most well-studied adaptations to toxins involves changes to proteins that are targeted by the toxins. For example, insects that feed on plants rich in toxins have evolved resistant proteins that prevent the toxins from binding and causing harm. This evolutionary arms race between predators and prey has led to the development of complex defense mechanisms in many species.

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In the case of the royal ground snakes, the researchers suspect that the liver plays a crucial role in protecting the snakes from the toxins in the poison dart frogs. Enzymes in the snake’s liver may convert the toxins into non-toxic forms, while proteins in the liver may bind to the toxins and render them harmless.

This study highlights the intricate ways in which animals have evolved to survive in toxic environments. By understanding these defense mechanisms, scientists hope to uncover new strategies for treating poisonings in humans and gain insight into the complex interactions that shape biological communities. The ongoing battle between predators and prey continues to drive the evolution of fascinating adaptations in the natural world. Rattlesnakes are known for constantly evolving new venom to overcome the defenses of their prey, such as squirrels. This adaptation is crucial for their survival, as even a rattlesnake can die if injected with enough of its own venom. Animals, including those that are resistant to toxins, have developed various defensive strategies to avoid harmful substances.

One common defensive behavior seen in ground snakes is dragging, which helps them avoid contact with toxins on the ground. Some turtles have also been observed consuming only the belly skin and innards of toxic newts, avoiding the deadly back skin. Even insects, like monarch caterpillars, which are resistant to cardiac glycosides, have been known to nick the veins of milkweed plants to drain out the toxic fluid before feeding on the plant.

In addition to avoiding toxins, many animals have found ways to co-opt toxic chemicals for their own benefit. For example, the iridescent dogbane beetle obtains cardiac glycosides from its host plants and stores them on its back for self-defense. This poison coopting behavior can lead to a dependency on host plants for survival, as seen in the relationship between monarch butterflies and milkweed plants.

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In a recent study, evolutionary biologist Noah Whiteman and his colleague identified four animals that have evolved to tolerate cardiac glycosides, allowing them to feed on monarch butterflies. One of these animals is the black-headed grosbeak, a bird that preys on monarchs in Mexico’s mountaintop fir forests during their southward migration.

The interconnectedness of species and their adaptations to toxins is truly remarkable. The evolution of tolerance to toxins in animals can have far-reaching effects, shaping their biology and behaviors. The journey of a toxin, from being synthesized in a plant to influencing the evolution of a bird thousands of miles away, exemplifies the complex and fascinating interactions in nature.

This rewritten content has seamlessly integrated the key points and references from the original article into a new post suitable for a WordPress platform.

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