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American Focus > Blog > Tech and Science > The cassette tape made a comeback in 2025 thanks to a DNA upgrade
Tech and Science

The cassette tape made a comeback in 2025 thanks to a DNA upgrade

Last updated: December 30, 2025 9:21 am
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The cassette tape made a comeback in 2025 thanks to a DNA upgrade
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The DNA tape can store vastly more information than a standard cassette

Jiankai Li et al. 2025

The Future of Data Storage: DNA Cassette Tapes

In a fascinating development, researchers have revolutionized data storage by creating a cutting-edge cassette tape that utilizes DNA instead of traditional materials like iron oxide to encode information on a plastic tape.

Unlike conventional cassette tapes that can store a limited number of songs, the DNA tape boasts an unprecedented capacity, capable of holding every song ever recorded. With each song requiring 10 megabytes, a staggering 100 meters of the DNA cassette tape can accommodate over 3 billion pieces of music, amounting to a total data storage capacity of 36 petabytes – equivalent to 36,000 terabyte hard drives.

Lead researcher Xingyu Jiang from the Southern University of Science and Technology in Guangdong, China, and his team engineered the cassette by imprinting synthetic DNA molecules onto a plastic tape. Jiang explained, “We can design its sequence so that the order of the DNA bases (A, T, C, G) represents digital information, just like 0s and 1s in a computer. This enables the tape to store any type of digital file, whether it be text, image, audio, or video.”

The researchers were pleasantly surprised by the widespread interest in their DNA cassette tape project after it was featured in New Scientist. Jiang expressed, “The diverse range of reactions we received, not only from scientists but also artists, engineers, and educators, was unexpected. Many individuals reached out to us, sharing how the work inspired them to think differently about data, biology, and technology. It was truly rewarding.”

See also  Obesity-Drug Pioneers Win Prestigious Lasker Award for Medical Science

Looking Ahead

The next phase for the team involves developing a new head for the DNA cassette, akin to the read-write head in a traditional magnetic tape drive. Jiang elaborated, “In our system, this ‘head’ precisely positions and presses a selected section of the DNA tape into a small reaction chamber, where chemical or biochemical processes – such as releasing, reading, or rewriting DNA – can take place.”

With ambitions to bring the DNA cassette tape to market within five years, Jiang emphasized, “For us, the DNA cassette tape project goes beyond storage capacity. It signifies a reimagination of how information can exist in physical, even biological, forms.”

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