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American Focus > Blog > Health and Wellness > Weightlifting outmuscles running for blood sugar control, study finds
Health and Wellness

Weightlifting outmuscles running for blood sugar control, study finds

Last updated: November 3, 2025 2:00 pm
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Weightlifting outmuscles running for blood sugar control, study finds
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A recent study conducted by the Fralin Biomedical Research Institute at Virginia Tech has shed light on the benefits of weightlifting versus running when it comes to preventing diabetes and obesity. The findings, published in the Journal of Sport and Health Science, compared the effects of endurance and resistance exercise in mice fed a high-fat diet, a common model for obesity and diabetes.

Lead researcher Zhen Yan and his team discovered that while both running and weightlifting helped clear excess sugar from the blood, resistance training was more effective in reducing subcutaneous and visceral fat, improving glucose tolerance, and lowering insulin resistance – all crucial factors in managing diabetes.

The study utilized a novel mouse model of weightlifting, where mice had to lift a weighted lid to access food, mimicking the muscle contractions used during resistance exercise. For the endurance group, mice had access to a running wheel. Over eight weeks, the researchers monitored various parameters such as weight gain, body composition, fat distribution, exercise capacity, and insulin signaling in skeletal muscle tissue.

The results showed that both running and weightlifting had positive effects on fat reduction and blood glucose maintenance, with weightlifting outperforming running in these health benefits. These findings are significant in the fight against diabetes and obesity, as they provide valuable insights into the effectiveness of different types of exercise.

The study also highlighted changes in skeletal muscle signaling pathways that could lead to new drug therapies for type 2 diabetes. Despite the benefits of resistance training not being solely attributed to changes in muscle mass or exercise performance, the metabolic mechanisms at play suggest unique benefits of weightlifting.

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Yan emphasized the importance of a well-balanced exercise program that includes both endurance and resistance training for maximum health benefits. While drug interventions like GLP-1 agonists can aid in diabetes management, they do not replace the comprehensive benefits of regular exercise.

In conclusion, the study underscores the importance of incorporating both types of exercise into one’s routine to achieve optimal health outcomes. The findings offer hope for individuals who may not be able to engage in endurance exercise, as weightlifting has been shown to have equal, if not better, anti-diabetes benefits. This research adds to the growing body of evidence supporting the positive impact of exercise on overall health and well-being.

TAGGED:bloodcontrolfindsoutmusclesrunningStudySugarWeightLifting
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